CAS 1622-32-8|2-Chloroethanesulfonyl chloride

Introduction：Basic information about CAS 1622-32-8|2-Chloroethanesulfonyl chloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles2
7. Synonyms

Common Name	2-Chloroethanesulfonyl chloride
CAS Number	1622-32-8	Molecular Weight	163.023
Density	1.5±0.1 g/cm3	Boiling Point	202.4±13.0 °C at 760 mmHg
Molecular Formula	C₂H₄Cl₂O₂S	Melting Point	/
MSDS	ChineseUSA	Flash Point	76.2±19.8 °C
Symbol	GHS05, GHS06	Signal Word	Danger

Names

Name	2-Chloroethanesulfonyl Chloride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	202.4±13.0 °C at 760 mmHg
Molecular Formula	C₂H₄Cl₂O₂S
Molecular Weight	163.023
Flash Point	76.2±19.8 °C
Exact Mass	161.930908
PSA	42.52000
LogP	0.83
Vapour Pressure	0.4±0.4 mmHg at 25°C
Index of Refraction	1.477
InChIKey	VHCSBTPOPKFYIU-UHFFFAOYSA-N
SMILES	O=S(=O)(Cl)CCCl

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI8060000

CHEMICAL NAME :: Ethanesulfonyl chloride, 2-chloro-

CAS REGISTRY NUMBER :: 1622-32-8

BEILSTEIN REFERENCE NO. :: 1751202

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C2-H4-Cl2-O2-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(6),59,1971

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 420 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(6),59,1971

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(6),59,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 mg/m3/4H/17W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Vascular - BP lowering not characterized in autonomic section

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(6),59,1971

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10 mg/m3/4H/17W-I

TOXIC EFFECTS :: Vascular - BP lowering not characterized in autonomic section Liver - liver function tests impaired Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 15(6),59,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 0.3 mg/m3;Skin JAN 1993

Safety Information

Symbol	GHS05, GHS06
Signal Word	Danger
Hazard Statements	H301-H314-H330
Precautionary Statements	P260-P280-P284-P301 + P310-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T+: Very toxic;
Risk Phrases	R22
Safety Phrases	S26-S28-S36/37/39-S45
RIDADR	UN 3390 6.1/PG 1
WGK Germany	3
RTECS	KI8060000
Packaging Group	II
Hazard Class	8
HS Code	2904909090

Customs

HS Code	2904909090
Summary	HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles2

Synthesis of a Library of 1,5,2-Dithiazepine 1,1-Dioxides. Part 1: A One-Pot Sulfonylation/Thia-Michael Protocol.

Heterocycles 86(2) , doi:10.3987/COM-12-S(N)121, (2012)

A novel one-pot sulfonylation/intramolecular thia-Michael protocol is reported for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. Sulfonylation between cysteine ethyl ester/cysteamine and 2-chloroe...

Thermal and high pressure intramolecular Diels-Alder reaction of vinylsulfonamides.

Nat. Protoc. 1(6) , 3076-87, (2006)

Vinylsulfonamides with a furan, carbocyclic, semicyclic or acyclic 1,3-diene moiety are synthetized via a domino elimination-amidation reaction of 2-chloroethanesulfonyl chloride. Intramolecular Diels...

Synonyms

Ethanesulfonylchloride, 2-chloro-

2-Chloroethanesulfonylchloride

Ethanesulfonyl chloride, 2-chloro-

2-CHLOROETHANE SULFOCHLORIDE

EINECS 216-594-1

MFCD00007461

2-Chloroethanesulfonyl chloride

2-Chloroethylsulfonyl chloride

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