CAS 132201-33-3|N-Benzoyl-(2R,3S)-3-phenylisoserine

Introduction：Basic information about CAS 132201-33-3|N-Benzoyl-(2R,3S)-3-phenylisoserine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. N-Benzoyl-(2R,3S)-3-phenylisoserine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles8
6. Synonyms

Common Name	N-Benzoyl-(2R,3S)-3-phenylisoserine
CAS Number	132201-33-3	Molecular Weight	285.29500
Density	1.316g/cm3	Boiling Point	580.7ºC at 760 mmHg
Molecular Formula	C₁₆H₁₅NO₄	Melting Point	169-172 °C(lit.)
MSDS	ChineseUSA	Flash Point	305ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	(2R,3S)-N-Benzoyl-3-phenyl Isoserine
Synonym	More Synonyms

N-Benzoyl-(2R,3S)-3-phenylisoserine BiologicalActivity

Description	N-Benzoyl-(2R,3S)-3-phenylisoserine is a Taxol C-13 Side Chain and crucial for the strong antitumor activity of Taxol[1].
Related Catalog	Signaling Pathways >>Others >>OthersNatural Products >>OthersResearch Areas >>Cancer
References	[1]. Iwao Ojima, et al. Efficient and Practical Asymmetric Synthesis of the Taxol C-13 Side Chain, N-Benzoyl-(2R,3S)-3-phenylisoserinea,n d Its Analogues via Chiral3-Hydroxy-4-aryl-&lactams through Chiral Ester Enolate-Imine Cyclocondensation.

Chemical & Physical Properties

Density	1.316g/cm3
Boiling Point	580.7ºC at 760 mmHg
Melting Point	169-172 °C(lit.)
Molecular Formula	C₁₆H₁₅NO₄
Molecular Weight	285.29500
Flash Point	305ºC
Exact Mass	285.10000
PSA	86.63000
LogP	1.99410
Vapour Pressure	2.51E-14mmHg at 25°C
Index of Refraction	1.625
InChIKey	HYJVYOWKYPNSTK-UONOGXRCSA-N
SMILES	O=C(NC(c1ccccc1)C(O)C(=O)O)c1ccccc1
Storage condition	-20℃

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3

Articles8

Kingston, D.G.I. et al.

J. Nat. Prod. 53 , 1, (1990)

Mangatal, L. et al.

Tetrahedron 45 , 4177, (1989)

Borman, S.

Chem. Eng. News 69(35) , 11, (1991)

Synonyms

(2R,3S)-3-benzamido-2-hydroxy-3-phenylpropanoic acid

MFCD00274633

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