CAS 25351-24-0|N-(2,5-Dihydroxybenzoyl)glycine

Introduction：Basic information about CAS 25351-24-0|N-(2,5-Dihydroxybenzoyl)glycine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. N-(2,5-Dihydroxybenzoyl)glycine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	N-(2,5-Dihydroxybenzoyl)glycine
CAS Number	25351-24-0	Molecular Weight	211.17
Density	1.532g/cm3	Boiling Point	530.1ºC at 760mmHg
Molecular Formula	C₉H₉NO₅	Melting Point	/
MSDS	ChineseUSA	Flash Point	274.4ºC
Symbol	GHS05, GHS07	Signal Word	Danger

Names

Name	2-[(2,5-dihydroxybenzoyl)amino]acetic acid
Synonym	More Synonyms

N-(2,5-Dihydroxybenzoyl)glycine BiologicalActivity

Description	Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316)[1][2].
Related Catalog	Research Areas >>Cancer
References	[1]. DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383(1):46-55. [2]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):113-9.

Description

Gentisuric acid, a metabolite of Aspirin (HY-14654), is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C (HY-13316)[1][2].

Related Catalog

Research Areas >>Cancer

References

[1]. DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383(1):46-55.

[2]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):113-9.

Chemical & Physical Properties

Density	1.532g/cm3
Boiling Point	530.1ºC at 760mmHg
Molecular Formula	C₉H₉NO₅
Molecular Weight	211.17
Flash Point	274.4ºC
Exact Mass	211.04800
PSA	106.86000
LogP	0.30310
Vapour Pressure	4.58E-12mmHg at 25°C
Index of Refraction	1.643
InChIKey	FBFATOOJCPDQOZ-UHFFFAOYSA-N
SMILES	O=C(O)CNC(=O)c1cc(O)ccc1O

Safety Information

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H315-H318-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
RIDADR	NONH for all modes of transport
HS Code	2918290000

Customs

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Gentisuric acid

Gentisuric Acid

N-(2,5-Dihydroxybenzoyl)glycine

2,5-Dihydroxyhippuric acid

2,5-Dihydroxybenzoyl-N-glycine

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