CAS 1662-06-2|(20R)-17,20-Dihydroxypregn-4-en-3-one

Introduction:Basic information about CAS 1662-06-2|(20R)-17,20-Dihydroxypregn-4-en-3-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(20R)-17,20-Dihydroxypregn-4-en-3-one
CAS Number1662-06-2Molecular Weight332.48
Density1.2±0.1 g/cm3Boiling Point487.1±45.0 °C at 760 mmHg
Molecular FormulaC21H32O3Melting Point201-202ºC
MSDSUSAFlash Point262.5±25.2 °C

Names

Name(20R)-17,20-dihydroxypregn-4-en-3-one
SynonymMore Synonyms

(20R)-17,20-Dihydroxypregn-4-en-3-one BiologicalActivity

Description17α,20β-Dihydroxy-4-pregnen-3-one (17,20β-P) is a maturation-inducing steroid[1].
Related CatalogResearch Areas >>EndocrinologySignaling Pathways >>Others >>Others
References

[1]. J V Planas, et al. Maturation-associated changes in the response of the salmon testis to the steroidogenic actions of gonadotropins (GTH I and GTH II) in vitro. Biol Reprod. 1995 Mar;52(3):697-704.  

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point487.1±45.0 °C at 760 mmHg
Melting Point201-202ºC
Molecular FormulaC21H32O3
Molecular Weight332.48
Flash Point262.5±25.2 °C
Exact Mass332.235138
PSA57.53000
LogP2.88
Vapour Pressure0.0±2.8 mmHg at 25°C
Index of Refraction1.568
InChIKeyMASCESDECGBIBB-FSHQYNQFSA-N
SMILESCC(O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C
Storage condition2-8°C

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Articles25

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Changes in expression of genes encoding gonadotropin subunits and growth hormone/prolactin/somatolactin family hormones during final maturation and freshwater adaptation in prespawning chum salmon.

Endocrine 20(1-2) , 23-34, (2003)

The pituitary levels of mRNAs encoding gonadotropin (GTH) subunits (GTH alpha2 and IIbeta), prolactin (PRL), and somatolactin (SL) increased in chum salmon during the last stages of spawning migration...

Dispersion of cyclin B mRNA aggregation is coupled with translational activation of the mRNA during zebrafish oocyte maturation.

Dev. Biol. 229(2) , 421-31, (2001)

Cyclin B mRNA stored in immature zebrafish oocytes is translationally activated upon the stimulation of 17alpha,20beta-dihydroxy-4-pregnen-3-one (17alpha,20beta-DP), an event prerequisite for initiati...

Epidermal growth factor receptor binding and biological activity in the ovary of goldfish, Carassius auratus.

Am. J. Physiol. 270(5 Pt 2) , R1065-72, (1996)

The receptor binding and biological activity of epidermal growth factor-urogastrone (EGF) was characterized in the follicle-enclosed goldfish oocyte. The binding of 125I-labeled mouse EGF (mEGF) to go...

Synonyms

(20R)-17,20-Dihydroxypregn-4-en-3-one
17ALPHA,20BETA-DIHYDROXY-4-PREGNEN-3-ONE
Pregn-4-en-3-one, 17,20-dihydroxy-, (20R)-
4-Pregnen-17α,20β-diol-3-one
MFCD00010485
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