CAS 185517-21-9|ONO 2506

Introduction:Basic information about CAS 185517-21-9|ONO 2506, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameONO 2506
CAS Number185517-21-9Molecular Weight186.29100
Density0.908 g/cm3Boiling Point289.3ºC at 760mmHg
Molecular FormulaC11H22O2Melting Point/
MSDS/Flash Point/

Names

Namearundic acid
SynonymMore Synonyms

ONO 2506 BiologicalActivity

DescriptionArundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid (ONO-2506) has been developed as a therapeutic agent for stroke and Alzheimer’s disease[1][2][3].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease
References

[1]. Tomoyuki Hasegawa, et al. Process Development of ONO-2506:  A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.

[2]. Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.

Chemical & Physical Properties

Density0.908 g/cm3
Boiling Point289.3ºC at 760mmHg
Molecular FormulaC11H22O2
Molecular Weight186.29100
Exact Mass186.16200
PSA37.30000
LogP3.45770
Vapour Pressure0.000557mmHg at 25°C
Index of Refraction1.444
InChIKeyYCYMCMYLORLIJX-SNVBAGLBSA-N
SMILESCCCCCCC(CCC)C(=O)O

Synonyms

2R-propyloctanoic acid
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