Introduction：Basic information about CAS 25875-51-8|Robenidine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Robenidine hydrochloride |
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| CAS Number | 25875-51-8 | Molecular Weight | 334.20 |
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| Density | 1.33 g/cm3 | Boiling Point | 488.1ºC at 760 mmHg |
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| Molecular Formula | C15H13Cl2N5 | Melting Point | / |
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| MSDS | / | Flash Point | 249ºC |
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Names
| Name | 1,2-bis[(E)-(4-chlorophenyl)methylideneamino]guanidine |
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| Synonym | More Synonyms |
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Robenidine hydrochloride BiologicalActivity
| Description | Robenidine is a coccidiostat agent that can be used for the research of coccidiosis caused by parasites in the Eimeria genus[1]. |
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| Related Catalog | Research Areas >>Infection |
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| References | [1]. Krollenbrock A, et, al. Robenidine Analogues Are Potent Antimalarials in Drug-Resistant Plasmodium falciparum. ACS Infect Dis. 2021 Jul 9;7(7):1956-1968. |
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Chemical & Physical Properties
| Density | 1.33 g/cm3 |
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| Boiling Point | 488.1ºC at 760 mmHg |
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| Molecular Formula | C15H13Cl2N5 |
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| Molecular Weight | 334.20 |
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| Flash Point | 249ºC |
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| Exact Mass | 333.05500 |
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| PSA | 72.63000 |
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| LogP | 4.35690 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.634 |
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| InChIKey | MOOFYEJFXBSZGE-UHFFFAOYSA-N |
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| SMILES | NC(=NN=Cc1ccc(Cl)cc1)NN=Cc1ccc(Cl)cc1 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- ME8650000
- CHEMICAL NAME :
- Guanidine, 1,3-bis((p-chlorobenzylidene)amino)-
- CAS REGISTRY NUMBER :
- 25875-51-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C15-H13-Cl2-N5
- MOLECULAR WEIGHT :
- 334.23
- WISWESSER LINE NOTATION :
- GR D1 UNMYUM&MNU1R DG
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1350 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1212 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 53(11),69,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1245 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - duck
- DOSE/DURATION :
- 1017 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- VETNAL Veterinariya. Veterinary Science. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1924- Volume(issue)/page/year: 57(9),53,1981
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Synonyms
| Khimcoccid |
| Chimcoccide |
| Khimkoktsid |
| Robenidine |
| Khimkoktside |
| Robenidine hydrochloride |
| EINECS 247-308-3 |
