Introduction：Basic information about CAS 163619-04-3|Fmoc-D-Trp(Boc)-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fmoc-D-Trp(Boc)-OH |
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| CAS Number | 163619-04-3 | Molecular Weight | 526.580 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C31H30N2O6 | Melting Point | 86 - 92ºC (Decomposes) |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid |
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| Synonym | More Synonyms |
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Fmoc-D-Trp(Boc)-OH BiologicalActivity
| Description | Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs). |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Melting Point | 86 - 92ºC (Decomposes) |
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| Molecular Formula | C31H30N2O6 |
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| Molecular Weight | 526.580 |
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| Exact Mass | 526.210388 |
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| PSA | 106.86000 |
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| LogP | 7.05 |
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| Index of Refraction | 1.632 |
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| InChIKey | ADOHASQZJSJZBT-AREMUKBSSA-N |
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| SMILES | CC(C)(C)OC(=O)n1cc(CC(NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c2ccccc21 |
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| Storage condition | 2-8°C |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn |
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| Safety Phrases | S22-S24/25 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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Articles1
More Articles
| Solid-phase synthesis of C-terminal azapeptides. J. Pept. Sci. 21 , 387-91, (2015) The solid-phase synthesis of azapeptides possessing a C-terminal aza-residue has been accomplished by a protocol featuring regioselective alkylation of benzhydrylidene-aza-glycinamide and illustrated ... | |
Synonyms
| 1-(tert-Butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan |
| Nalpha-Fmoc-N(in)-Boc-D-tryptophan |
| AmbotzFAA1339 |
| Fmoc-D-Trp(Boc) |
| N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-tryptophan |
| D-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- |
| Fmoc-D-Trp(Boc)-OH |
| N|A-Fmoc-N(in)-Boc-D-tryptophan |
| Fmoc-L-Trp(Boc)-OH |
| MFCD00153367 |
| (2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid |
