CAS 39432-56-9|Eleutheroside E

Introduction：Basic information about CAS 39432-56-9|Eleutheroside E, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Eleutheroside E BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles15
6. Synonyms

Common Name	Eleutheroside E
CAS Number	39432-56-9	Molecular Weight	742.718
Density	1.5±0.1 g/cm3	Boiling Point	935.7±65.0 °C at 760 mmHg
Molecular Formula	C₃₄H₄₆O₁₈	Melting Point	255 - 260ºC
MSDS	ChineseUSA	Flash Point	519.7±34.3 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	Eleutheroside E
Synonym	More Synonyms

Eleutheroside E BiologicalActivity

Description	Eleutheroside E, a principal component of Eleutherococcus enticosus, has anti-inflammatory and protective effects in ischemia heart. IC50 value:Target:In vitro: Treatment of 10 μM Eleutheroside E (EE) for 24 h increased basal glucose uptake as well as improved TNF-α-mediated suppression of glucose uptake. [2]In vivo: To investigate the effect of Eleutheroside E (EE) on arthritis, the CIA model in DBA/1 mice was used. Compared to vehicle-treated CIA mice, 15 mg/kg TG treatment and 30 and 60 mg/kg EE treatment obviously decreased the arthritis scores and body weight loss in CIA mice (P<0.01) [1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyNatural Products >>Terpenoids and Glycosides
References	[1]. Chunyan He, et al. Eleutheroside E Ameliorates Arthritis Severity in Collagen-Induced Arthritis Mice Model by Suppressing Inflammatory Cytokine Release. Inflammation, Vol. 37, No. 5, October 2014 (# 2014) [2]. Jiyun Ahn, et al. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice. Evid Based Complement Alternat Med. 2013; 2013: 934183.

Description

Eleutheroside E, a principal component of Eleutherococcus enticosus, has anti-inflammatory and protective effects in ischemia heart. IC50 value:Target:In vitro: Treatment of 10 μM Eleutheroside E (EE) for 24 h increased basal glucose uptake as well as improved TNF-α-mediated suppression of glucose uptake. [2]In vivo: To investigate the effect of Eleutheroside E (EE) on arthritis, the CIA model in DBA/1 mice was used. Compared to vehicle-treated CIA mice, 15 mg/kg TG treatment and 30 and 60 mg/kg EE treatment obviously decreased the arthritis scores and body weight loss in CIA mice (P<0.01) [1].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/ImmunologyNatural Products >>Terpenoids and Glycosides

References

[1]. Chunyan He, et al. Eleutheroside E Ameliorates Arthritis Severity in Collagen-Induced Arthritis Mice Model by Suppressing Inflammatory Cytokine Release. Inflammation, Vol. 37, No. 5, October 2014 (# 2014)

[2]. Jiyun Ahn, et al. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice. Evid Based Complement Alternat Med. 2013; 2013: 934183.

Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	935.7±65.0 °C at 760 mmHg
Melting Point	255 - 260ºC
Molecular Formula	C₃₄H₄₆O₁₈
Molecular Weight	742.718
Flash Point	519.7±34.3 °C
Exact Mass	742.268433
PSA	254.14000
LogP	-3.91
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.616
InChIKey	FFDULTAFAQRACT-JSGUJALWSA-N
SMILES	COc1cc(C2OCC3C(c4cc(OC)c(OC5OC(CO)C(O)C(O)C5O)c(OC)c4)OCC23)cc(OC)c1OC1OC(CO)C(O)C(O)C1O
Storage condition	2-8°C

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Hazard Codes	Xn
Risk Phrases	22
Safety Phrases	24/25
RIDADR	NONH for all modes of transport

Articles15

[Studies on chemical constituents from stem barks of Fraxinus paxiana].

Zhongguo Zhong Yao Za Zhi 33(16) , 1990-3, (2008)

To investigate the chemical constituents of Fraxinus paxiana.The chemical constituents were isolated and purified by chromatographic techniques and the structures of the compounds were identified with...

[Chemical constituents from flowers of Chrysanthemum indicum].

Zhongguo Zhong Yao Za Zhi 35(6) , 718-21, (2010)

To investigate the chemical constituents of the flowers of Chrysanthemum indicum.The chemical constituents were isolated by various column chromatographic methods. The structures were identified by sp...

[Studies on phenylpropanoids from herbs of Eriophyton wallichii].

Zhongguo Zhong Yao Za Zhi 33(22) , 2636-9, (2008)

To study the chemical constituents of Eriophyton wallichii.Compounds were separated and purified by column chromatographic methods, and their structures were elucidated by spectroscopic methods.Eight ...

Synonyms

4-{(1R,3aR,4S,6aS)-4-[4-(β-L-Glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl}-2,6-dimethoxyphenyl β-D-glucopyranoside

β-D-Glucopyranoside, 4-[(1R,3aR,4S,6aS)-4-[4-(β-L-glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2,6-dimethoxyphenyl

β-D-Glucopyranoside, 4-[(1R,3aS,4S,6aR)-4-[4-(β-L-glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2,6-dimethoxyphenyl

(2R,3S,4R,5R,6S)-2-[4-[6-[3,5-dimethoxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2,6-dimethoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

4-{(1R,3aS,4S,6aR)-4-[4-(β-L-Glucopyranosyloxy)-3,5-dimethoxyphenyl]tetrahydro-1H,3H-furo[3,4-c]furan-1-yl}-2,6-dimethoxyphenyl β-D-glucopyranoside

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