Introduction：Basic information about CAS 364-76-1|4-Fluoro-3-nitroaniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Fluoro-3-nitroaniline |
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| CAS Number | 364-76-1 | Molecular Weight | 156.115 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 331.3±22.0 °C at 760 mmHg |
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| Molecular Formula | C6H5FN2O2 | Melting Point | 94-96 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 91.1±0.0 °C |
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| Symbol |
GHS07 | Signal Word | Warning |
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Names
| Name | 4-fluoro-3-nitroaniline |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 331.3±22.0 °C at 760 mmHg |
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| Melting Point | 94-96 °C(lit.) |
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| Molecular Formula | C6H5FN2O2 |
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| Molecular Weight | 156.115 |
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| Flash Point | 91.1±0.0 °C |
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| Exact Mass | 156.033508 |
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| PSA | 71.84000 |
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| LogP | 1.27 |
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| Vapour Pressure | 0.0±0.7 mmHg at 25°C |
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| Index of Refraction | 1.603 |
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| InChIKey | LLIOADBCFIXIEU-UHFFFAOYSA-N |
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| SMILES | Nc1ccc(F)c([N+](=O)[O-])c1 |
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| Water Solubility | Insoluble |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- BY1700000
- CHEMICAL NAME :
- Aniline, 4-fluoro-3-nitro-
- CAS REGISTRY NUMBER :
- 364-76-1
- BEILSTEIN REFERENCE NO. :
- 2210199
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C6-H5-F-N2-O2
- MOLECULAR WEIGHT :
- 156.13
- WISWESSER LINE NOTATION :
- ZR DF CNW
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,400,1984
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >200 gm/m3/1H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,400,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,400,1984 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1080 mg/kg/90D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in bladder weight Blood - change in clotting factors Blood - changes in erythrocyte (RBC) count
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 72,400,1984
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Safety Information
| Symbol |
GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H302 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xn:Harmful |
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| Risk Phrases | R22;R36/37/38 |
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| Safety Phrases | S36/37-S37/39-S26 |
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| RIDADR | UN 1325 4.1/PG 2 |
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| WGK Germany | 2 |
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| RTECS | BY1700000 |
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| Packaging Group | III |
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| Hazard Class | 6.1(b) |
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| HS Code | 29214210 |
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Customs
| HS Code | 2921420090 |
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| Summary | HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Articles2
More Articles
| Inhibition of monoamine oxidase by phenyl azides. J. Neurochem. 45(3) , 940-5, (1985) We had previously shown that 4-fluoro-3-nitrophenyl azide (FNPA) is a competitive inhibitor of both types of monoamine oxidase (MAO) in the dark, but it is a preferential photoaffinity label for only ... | |
| Subchronic oral toxicology of 4-fluoro-3-nitroaniline in the rat. Toxicol. Appl. Pharmacol. 72(3) , 400-5, (1984) 4-Fluoro-3-nitroaniline (4-F-3-NA), an intermediate used in the production of commercial hair dyes, was administered daily for 90 days via po intubation to Charles River CD rats at doses of 40, 120, o... | |
Synonyms
| 4-Fluoro-3-nitro-phenylamine |
| 4-Fluoro-3-nitrobenzenamine |
| 3-nitro-4-fluoroaniline |
| 4-Fluoro-3-nitroaniline |
| EINECS 206-665-5 |
| 3-nitro-4-fluoroanailine |
| 4-amino-1-fluoro-2-nitrobenzene |
| 4-fluoro-5-nitroaniline |
| Benzenamine,4-fluoro-3-nitro |
| 5-amino-2-fluoronitrobenzene |
| MFCD00007833 |
| Benzenamine, 4-fluoro-3-nitro- |
| 4'-fluoro-3'-nitroaniline |
| ZR DF CNW |
| Aniline,4-fluoro-3-nitro |
| 4-Amino-2-nitrofluorobenzene |
