Introduction：Basic information about CAS 169105-89-9|5-epi-Isofagomine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-epi-Isofagomine |
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| CAS Number | 169105-89-9 | Molecular Weight | 147.17 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 317.2±37.0 °C at 760 mmHg |
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| Molecular Formula | C6H13NO3 | Melting Point | / |
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| MSDS | / | Flash Point | 171.8±17.1 °C |
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Names
| Name | (3R,4R,5R)-5-(hydroxymethyl)piperidine-3,4-diol |
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| Synonym | More Synonyms |
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5-epi-Isofagomine BiologicalActivity
| Description | Afegostat was previously in phase II clinical trials for the treatment of Gaucher's disease. The experiment was discontinued. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Richter F, et al. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct;11(4):840-56. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 317.2±37.0 °C at 760 mmHg |
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| Molecular Formula | C6H13NO3 |
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| Molecular Weight | 147.17 |
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| Flash Point | 171.8±17.1 °C |
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| PSA | 72.72000 |
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| LogP | -1.80 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.535 |
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| InChIKey | QPYJXFZUIJOGNX-HSUXUTPPSA-N |
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| SMILES | OCC1CNCC(O)C1O |
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Synonyms
| IFM |
| 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE |
| (3R,4R,5S)-5-(Hydroxymethyl)piperidine-3,4-diol |
| 5-epi-Isofagomine |
| 3,4-Piperidinediol, 5-(hydroxymethyl)-, (3R,4R,5S)- |
| iso-Fagomine |
| (3R,4R,5S)-5-(Hydroxymethyl)-3,4-piperidinediol |
| 1oif |
| D-Isofagomine |
| Afegostat |
