CAS 313-04-2|Desmesterol
| Common Name | Desmesterol | ||
|---|---|---|---|
| CAS Number | 313-04-2 | Molecular Weight | 384.638 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 483.2±14.0 °C at 760 mmHg |
| Molecular Formula | C27H44O | Melting Point | 121.5ºC |
| MSDS | ChineseUSA | Flash Point | 209.2±12.4 °C |
Names
| Name | desmosterol |
|---|---|
| Synonym | More Synonyms |
Desmesterol BiologicalActivity
| Description | Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism[1]. |
|---|---|
| Related Catalog | Research Areas >>Metabolic Disease |
| Target | Human Endogenous Metabolite |
| References | [1]. Clark RM, et al. Desmosterol in human milk. Lipids. 1983;18(3):264-266. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 483.2±14.0 °C at 760 mmHg |
| Melting Point | 121.5ºC |
| Molecular Formula | C27H44O |
| Molecular Weight | 384.638 |
| Flash Point | 209.2±12.4 °C |
| Exact Mass | 384.339203 |
| PSA | 20.23000 |
| LogP | 9.54 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.536 |
| InChIKey | AVSXSVCZWQODGV-DPAQBDIFSA-N |
| SMILES | CC(C)=CCCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C |
| Storage condition | -20°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
Articles70
More Articles| A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids. J. Chromatogr. A. 1371 , 184-95, (2014) Recently, hydroxy sterols and bile acids have gained growing interest as they are important regulators of energy homoeostasis and inflammation. The high number of different hydroxy sterols and bile ac... | |
| Sterol Composition in Infant Formulas and Estimated Intake. J. Agric. Food Chem. 63 , 7245-51, (2015) Sterol contents in infant formulas (IFs) from the European market were determined, and their intakes by infants between 0 and 6 months were evaluated. Total animal sterols (mg/100 mL) ranged from 1.71... | |
| Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development. Hum. Mol. Genet. 24 , 2808-25, (2015) NSDHL is a 3β-hydroxysterol dehydrogenase that is involved in the removal of two C-4 methyl groups in one of the later steps of cholesterol biosynthesis. Mutations in the gene encoding the enzyme are ... |
Synonyms
| cholest-5,24-dien-3β-ol |
| Desmosterol |
| Cholesta-5,24-dien-3b-ol |
| Desmesterol |
| Cholesta-5,24-dien-3-β-ol |
| 3b-Cholesta-5,24-dien-3-ol |
| EINECS 206-236-2 |
| Cholesta-5,24-dien-3-ol, (3β)- |
| MFCD00056432 |
| 3ß-hydroxy-5,24-cholestadiene |
| Cholesta-5,24-dien-3β-ol (8CI) |
| (3β)-Cholesta-5,24-dien-3-ol |
| (3β,20R)-Cholesta-5,24-dien-3-ol |
| Cholesta-5,24-dien-3-ol, (3β,20R)- |
| Cholesta-5,24-dien-3β-ol |
| 5,24-cholestadien-3β-ol |
