CAS 314-03-4|Pimethixene

Introduction：Basic information about CAS 314-03-4|Pimethixene, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Pimethixene BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Synonyms

Common Name	Pimethixene
CAS Number	314-03-4	Molecular Weight	293.42600
Density	1.192g/cm3	Boiling Point	439.7ºC at 760mmHg
Molecular Formula	C₁₉H₁₉NS	Melting Point	/
MSDS	/	Flash Point	219.7ºC

Names

Name	pimethixene
Synonym	More Synonyms

Pimethixene BiologicalActivity

Description	Pimethixene is an antihistamine and anticholinergic agent, that is often used to treat hyperactivity, anxiety, sleep disorders, and allergy.
Related Catalog	Signaling Pathways >>Neuronal Signaling >>AChESignaling Pathways >>GPCR/G Protein >>Histamine ReceptorSignaling Pathways >>Immunology/Inflammation >>Histamine ReceptorResearch Areas >>Neurological Disease

Chemical & Physical Properties

Density	1.192g/cm3
Boiling Point	439.7ºC at 760mmHg
Molecular Formula	C₁₉H₁₉NS
Molecular Weight	293.42600
Flash Point	219.7ºC
Exact Mass	293.12400
PSA	28.54000
LogP	4.61660
Index of Refraction	1.661
InChIKey	NZLVRVYNQYGMAB-UHFFFAOYSA-N
SMILES	CN1CCC(=C2c3ccccc3Sc3ccccc32)CC1
Storage condition	2-8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN1575000

CHEMICAL NAME :: Piperidine, 1-methyl-4-thioxanthen-9-ylidene-

CAS REGISTRY NUMBER :: 314-03-4

LAST UPDATED :: 199707

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C19-H19-N-S

MOLECULAR WEIGHT :: 293.45

WISWESSER LINE NOTATION :: T C666 BS IYJ IU- DT6N DYTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 13 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 23 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 460 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,62,1972

Synonyms

Calmixene

10-(1-methyl-4-piperidylidene)dibenzo[b,e]thiane

1-methyl-4-(9H-thioxanthen-9-ylidene)-piperidine

1-methyl-4-thioxanthen-9-ylidene-piperidine

Calmixen

9-(N-methyl-piperidyliden-4-yl)-thioxanthene

9-(N-methyl-piperidyliden-4)-thioxanthene

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