Introduction：Basic information about CAS 163217-70-7|4-hydroxy Atorvastatin lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-hydroxy Atorvastatin lactone |
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| CAS Number | 163217-70-7 | Molecular Weight | 556.62 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C33H33FN2O5 | Melting Point | 103-106℃ |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(4-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide |
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| Synonym | More Synonyms |
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4-hydroxy Atorvastatin lactone BiologicalActivity
| Description | 4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologyResearch Areas >>Metabolic Disease |
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| References | [1]. Jemal M, et al. Quantitation of the acid and lactone forms of atorvastatin and its biotransformation products in human serum by high-performance liquid chromatography with electrospray tandem mass spectrometry. Rapid Commun Mass Spectrom. 1999;13(11):1003-15. |
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Chemical & Physical Properties
| Melting Point | 103-106℃ |
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| Molecular Formula | C33H33FN2O5 |
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| Molecular Weight | 556.62 |
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| Exact Mass | 556.23700 |
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| PSA | 100.79000 |
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| LogP | 6.57210 |
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| InChIKey | KDJMDZSAAFACAM-KAYWLYCHSA-N |
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| SMILES | CC(C)c1c(C(=O)Nc2ccc(O)cc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC1CC(O)CC(=O)O1 |
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Synonyms
| 5-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide |
| 4-Hydroxy Atorvastatin Lactone |
| UNII-1316I46GEX |
