Introduction：Basic information about CAS 4431-42-9|Isopedicin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Isopedicin |
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| CAS Number | 4431-42-9 | Molecular Weight | 330.33 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 552.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C18H18O6 | Melting Point | / |
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| MSDS | / | Flash Point | 202.8±23.6 °C |
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Names
| Name | 2,4,6-Trimethylbenzamide |
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| Synonym | More Synonyms |
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Isopedicin BiologicalActivity
| Description | Isopedicin potently and concentration-dependently inhibits superoxide anion (O2 U?) production in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated cells. Isopedicin increases cAMP formation and PKA activity in FMLP-activated cells by inhibiting phosphodiesterase (PDE) activity[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Phosphodiesterase (PDE)Research Areas >>Metabolic Disease |
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| References | [1]. Hwang TL, et al. Potent inhibition of superoxide anion production in activated human neutrophils by isopedicin, a bioactive component of the Chinese medicinal herb Fissistigma oldhamii. Free Radic Biol Med. 2009 Feb 15;46(4):520-8. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 552.9±50.0 °C at 760 mmHg |
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| Molecular Formula | C18H18O6 |
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| Molecular Weight | 330.33 |
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| Flash Point | 202.8±23.6 °C |
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| Exact Mass | 330.110352 |
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| PSA | 74.22000 |
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| LogP | 2.92 |
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| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
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| Index of Refraction | 1.584 |
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| InChIKey | CSVYPJWNGKLMJM-UHFFFAOYSA-N |
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| SMILES | COc1c(O)c(OC)c2c(c1OC)OC(c1ccccc1)CC2=O |
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Synonyms
| 6-Hydroxy-5,7,8-trimethoxy-2-phenyl-chroman-4-on |
| 4H-1-Benzopyran-4-one, 2,3-dihydro-6-hydroxy-5,7,8-trimethoxy-2-phenyl-, (2S)- |
| 6-Hydroxy-5,5-dimethyl-5,6-dihydro-benz<c>acridin |
| 5,5-Dimethyl-6-hydroxy-5,6-dihydrobenz<c>acridin |
| 6-hydroxy-5,7,8-trimethoxy-2-phenyl-chroman-4-one |
| (2S)-6-Hydroxy-5,7,8-trimethoxy-2-phenyl-2,3-dihydro-4H-chromen-4-one |
