Introduction：Basic information about CAS 133865-88-0|Ralfinamide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ralfinamide |
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| CAS Number | 133865-88-0 | Molecular Weight | 302.34300 |
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| Density | 1.189 | Boiling Point | 479ºC at 760mmHg |
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| Molecular Formula | C17H19FN2O2 | Melting Point | / |
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| MSDS | / | Flash Point | 243.5ºC |
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Names
| Name | (2S)-2-[[4-[(2-fluorophenyl)methoxy]phenyl]methylamino]propanamide |
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| Synonym | More Synonyms |
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Ralfinamide BiologicalActivity
| Description | Ralfinamide (FCE-26742A) is an orally available Na(+) channel blocker derived from α-aminoamide, with function of suppressing pain[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Sodium ChannelResearch Areas >>Neurological Disease |
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| Target | Sodium Channel[1] |
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| References | [1]. Zhang SH, et al. Ralfinamide administered orally before hindpaw neurectomy or postoperatively provided long-lasting suppression of spontaneous neuropathic pain-related behavior in the rat. Pain. 2008 Oct 15;139(2):293-305. [2]. Liang X, et al. Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain. Eur J Pharmacol. 2018 Mar 15;823:27-34. |
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Chemical & Physical Properties
| Density | 1.189 |
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| Boiling Point | 479ºC at 760mmHg |
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| Molecular Formula | C17H19FN2O2 |
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| Molecular Weight | 302.34300 |
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| Flash Point | 243.5ºC |
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| Exact Mass | 302.14300 |
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| PSA | 55.56000 |
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| LogP | 3.41500 |
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| Vapour Pressure | 2.46E-09mmHg at 25°C |
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| Index of Refraction | 1.569 |
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| InChIKey | BHJIBOFHEFDSAU-LBPRGKRZSA-N |
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| SMILES | CC(NCc1ccc(OCc2ccccc2F)cc1)C(N)=O |
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| Storage condition | 2-8°C |
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Safety Information
| Hazard Codes | T+ |
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| RIDADR | 2811.0 |
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| HS Code | 2924299090 |
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Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| UNII-3LPF0S0GVV |
| Ralfinamida |
| Ralfinamide |
| NW-1029 |
