Introduction：Basic information about CAS 31255-26-2|Bromo-PEG3-bromide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Bromo-PEG3-bromide |
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| CAS Number | 31255-26-2 | Molecular Weight | 320.01900 |
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| Density | 1.57 g/cm3at 25°C (lit.) | Boiling Point | 146 °C at 0.06 Torr (lit.) |
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| Molecular Formula | C8H16Br2O3 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 1-(2-bromoethoxy)-2-[2-(2-bromoethoxy)ethoxy]ethane |
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| Synonym | More Synonyms |
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Bromo-PEG3-bromide BiologicalActivity
| Description | Bromo-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.57 g/cm3at 25°C (lit.) |
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| Boiling Point | 146 °C at 0.06 Torr (lit.) |
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| Molecular Formula | C8H16Br2O3 |
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| Molecular Weight | 320.01900 |
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| Exact Mass | 317.94700 |
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| PSA | 27.69000 |
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| LogP | 1.82600 |
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| InChIKey | IJFMWHWXEBUOKR-UHFFFAOYSA-N |
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| SMILES | BrCCOCCOCCOCCBr |
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Safety Information
Synonyms
| 1,11-ibromo-3,6,9-trioxaundecane |
| 1,11-dibromo-3,6,9-trioxaundecane |
| 3,6,9-trioxa-1,11-dibromoundecane |
| 3,6,9-trioxaundecane-1,11-dibromide |
