Introduction：Basic information about CAS 250584-13-5|Z-Asp-Glu-Val-Asp-chloromethylketone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Z-Asp-Glu-Val-Asp-chloromethylketone |
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| CAS Number | 250584-13-5 | Molecular Weight | 643.04 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C27H35ClN4O12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | z-devd-cmk |
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| Synonym | More Synonyms |
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Z-Asp-Glu-Val-Asp-chloromethylketone BiologicalActivity
| Description | Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1]. |
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| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>Cathepsin |
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| Target | Papain, Cathepsins B, Cathepsins L, Cathepsins V, Cathepsins S, Cathepsins X[1] |
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| References | [1]. Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10(8):881-8. |
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Chemical & Physical Properties
| Molecular Formula | C27H35ClN4O12 |
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| Molecular Weight | 643.04 |
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| Exact Mass | 642.19400 |
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| PSA | 254.60000 |
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| LogP | 1.57750 |
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| InChIKey | GRXANEWUMQJHCJ-UHFFFAOYSA-N |
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| SMILES | CC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CCl |
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| Storage condition | -15°C |
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Synonyms
| Z-ASP-GLU-VAL-ASP-CMK |
| Z-ASP-GLU-VAL-ASP-CHLOROMETHYLKETONE |
| Z-Asp-Glu-Val-Asp-chloromethyketone |
