CAS 16564-43-5|Glycochenodeoxycholic acid sodium
| Common Name | Glycochenodeoxycholic acid sodium | ||
|---|---|---|---|
| CAS Number | 16564-43-5 | Molecular Weight | 471.605 |
| Density | / | Boiling Point | 655.6ºC at 760mmHg |
| Molecular Formula | C26H42NNaO5 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 350.3ºC |
Names
| Name | Glycochenodeoxycholic acid sodium |
|---|---|
| Synonym | More Synonyms |
Glycochenodeoxycholic acid sodium BiologicalActivity
| Description | Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid sodium salt (Chenodeoxycholylglycine sodium salt) induces hepatocyte apoptosis[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer |
| References | [1]. Liang S, et al. Effect of quercetin 7-rhamnoside on glycochenodeoxycholic acid-induced L-02 human normal livercell apoptosis. Int J Mol Med. 2013 Aug;32(2):323-30. [2]. Gonzalez B, et al. Glycochenodeoxycholic acid (GCDC) induced hepatocyte apoptosis is associated with early modulation of intracellular PKC activity. Mol Cell Biochem. 2000 Apr;207(1-2):19-27. |
Chemical & Physical Properties
| Boiling Point | 655.6ºC at 760mmHg |
|---|---|
| Molecular Formula | C26H42NNaO5 |
| Molecular Weight | 471.605 |
| Flash Point | 350.3ºC |
| Exact Mass | 471.296082 |
| PSA | 109.69000 |
| LogP | 2.65030 |
| Vapour Pressure | 5.74E-20mmHg at 25°C |
| InChIKey | AAYACJGHNRIFCT-VGGUSGIJSA-M |
| SMILES | CC(CCC(=O)NCC(=O)[O-])C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C.[Na+] |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3.0 |
| HS Code | 2924299090 |
Customs
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Sodium glycochenodeoxycholate |
| 3α,7α-Dihydroxy-5β-cholanoic acid N-(carboxymethyl)amide sodium salt |
| Sodium {[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]amino}acetate |
| Glycine, N-((3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl)-, monosodium salt |
| N-(3α,7α-Dihydroxy-24-oxocholan-24-yl)glycine sodium salt |
| Glycine, N-[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]-, sodium salt (1:1) |
| Glycochenodeoxycholic acid sodium salt |
