Introduction：Basic information about CAS 31137-74-3|SYM 2081, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | SYM 2081 |
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| CAS Number | 31137-74-3 | Molecular Weight | 161.16 |
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| Density | / | Boiling Point | 329.4ºC at 760mmHg |
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| Molecular Formula | C6H11NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 153ºC |
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Names
| Name | (2S,4R)-4-Methylglutamic Acid |
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| Synonym | More Synonyms |
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SYM 2081 BiologicalActivity
| Description | SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively[1]. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
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| Target | IC50: 35 nM (kainate receptors)[1] |
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| References | [1]. Lee JY, et al. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Nov;150(4):546-57. |
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Chemical & Physical Properties
| Boiling Point | 329.4ºC at 760mmHg |
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| Molecular Formula | C6H11NO4 |
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| Molecular Weight | 161.16 |
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| Flash Point | 153ºC |
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| Exact Mass | 161.06900 |
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| PSA | 100.62000 |
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| LogP | 0.20940 |
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| Appearance of Characters | solid | white |
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| Storage condition | Store at RT |
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| Water Solubility | H2O: >10 mg/mL |
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Safety Information
| WGK Germany | 3 |
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| HS Code | 2922499990 |
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Customs
| HS Code | 2922499990 |
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| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| (2S,4R)-4-Methylglutamic acid |
| (2S,4R)-2-azaniumyl-4-methylpentanedioate |
| MFCD00937765 |
