Introduction：Basic information about CAS 36457-20-2|Sodium 4-(butoxycarbonyl)phenolate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sodium 4-(butoxycarbonyl)phenolate |
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| CAS Number | 36457-20-2 | Molecular Weight | 216.209 |
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| Density | 1.13g/mL | Boiling Point | 309.2ºC at 760 mmHg |
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| Molecular Formula | C11H13NaO3 | Melting Point | / |
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| MSDS | / | Flash Point | 129.2ºC |
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Names
| Name | Butylparaben Sodium Salt |
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| Synonym | More Synonyms |
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Sodium 4-(butoxycarbonyl)phenolate BiologicalActivity
| Description | Butylparaben sodium strongly influences the later stages of the spermatogenesis in the testis through the deterioration of hormonal control and/or RNA and protein synthesis[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>OthersSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. Shinshi Oishi, et al. Effects of butyl paraben on the male reproductive system in mice. Arch Toxicol. 2002 Jul;76(7):423-9. [2]. Bae JS, et al. Thirteen-week subcutaneous repeated dose toxicity study of butylparaben and its toxicokinetics in rats. Arch Toxicol. 2021 Jun;95(6):2037-2050. |
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Chemical & Physical Properties
| Density | 1.13g/mL |
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| Boiling Point | 309.2ºC at 760 mmHg |
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| Molecular Formula | C11H13NaO3 |
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| Molecular Weight | 216.209 |
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| Flash Point | 129.2ºC |
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| Exact Mass | 216.076233 |
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| PSA | 49.36000 |
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| LogP | 2.78730 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DH2040000
- CHEMICAL NAME :
- Benzoic acid, p-hydroxy-, butyl ester, sodium salt
- CAS REGISTRY NUMBER :
- 36457-20-2
- LAST UPDATED :
- 199107
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C11-H13-O3.Na
- MOLECULAR WEIGHT :
- 216.23
- WISWESSER LINE NOTATION :
- QR DVO4 &-NA-
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 950 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956
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Safety Information
| RIDADR | 3077.0 |
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| Hazard Class | 9.0 |
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| HS Code | 2918990090 |
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Customs
| HS Code | 2918990090 |
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| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Synonyms
| Sodium 4-(butoxycarbonyl)phenolate |
| EINECS 253-049-7 |
| MFCD01661516 |
| sodium,4-butoxycarbonylphenolate |
| Benzoic acid, 4-hydroxy-, butyl ester, sodium salt (1:1) |
