Introduction：Basic information about CAS 163217-74-1|2-Hydroxy atorvastatin lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Hydroxy atorvastatin lactone |
|---|
| CAS Number | 163217-74-1 | Molecular Weight | 556.62400 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C33H33FN2O5 | Melting Point | 110-112ºC |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | 2-Hydroxy Atorvastatin Lactone |
|---|
| Synonym | More Synonyms |
|---|
2-Hydroxy atorvastatin lactone BiologicalActivity
| Description | 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2]. |
|---|
| Related Catalog | Research Areas >>Others |
|---|
| References | [1]. Guo CX, et al. Effects of Ginkgo biloba extracts on pharmacokinetics and efficacy of atorvastatin based on plasma indices. Xenobiotica. 2012;42(8):784‐790. [2]. Turner NA, et al. Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion. J Cardiovasc Pharmacol. 2007 Oct;50(4):458-61. |
|---|
Chemical & Physical Properties
| Melting Point | 110-112ºC |
|---|
| Molecular Formula | C33H33FN2O5 |
|---|
| Molecular Weight | 556.62400 |
|---|
| Exact Mass | 556.23700 |
|---|
| PSA | 100.79000 |
|---|
| LogP | 6.57210 |
|---|
| InChIKey | MNECBMZJZFGTIK-JWQCQUIFSA-N |
|---|
| SMILES | CC(C)c1c(C(=O)Nc2ccccc2O)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC1CC(O)CC(=O)O1 |
|---|
Synonyms
| 5-(4-fluorophenyl)-1-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-N-(2-hydroxyphenyl)-4-phenyl-2-propan-2-ylpyrrole-3-carboxamide |
