Introduction：Basic information about CAS 924296-17-3|DUBs-IN-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DUBs-IN-3 |
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| CAS Number | 924296-17-3 | Molecular Weight | 287.27600 |
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| Density | 1.31g/cm3 | Boiling Point | 560.4ºC at 760 mmHg |
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| Molecular Formula | C16H9N5O | Melting Point | / |
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| MSDS | / | Flash Point | 292.7ºC |
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Names
| Name | 9-[(Allyloxy)imino]-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile |
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| Synonym | More Synonyms |
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DUBs-IN-3 BiologicalActivity
| Description | DUBs-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c with an IC50 of 0.56 μM for USP8. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DeubiquitinaseResearch Areas >>Cancer |
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| Target | IC50: 0.56 μM (USP8)[1] |
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| References | [1]. Colombo M, et al. Synthesis and biological evaluation of 9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile analogues as potential inhibitors of deubiquitinating enzymes. ChemMedChem. 2010 Apr 6;5(4):552-8. |
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Chemical & Physical Properties
| Density | 1.31g/cm3 |
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| Boiling Point | 560.4ºC at 760 mmHg |
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| Molecular Formula | C16H9N5O |
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| Molecular Weight | 287.27600 |
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| Flash Point | 292.7ºC |
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| Exact Mass | 287.08100 |
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| PSA | 94.95000 |
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| LogP | 2.15536 |
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| Index of Refraction | 1.684 |
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| InChIKey | XLOXSIKLUAMDGU-RCCKNPSSSA-N |
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| SMILES | C=CCON=C1c2ccccc2-c2nc(C#N)c(C#N)nc21 |
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Synonyms
