Introduction：Basic information about CAS 61012-19-9|(Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH trifluoroacetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (Des-Gly10,tBu-D-Gly6,Pro-NHEt9)-LHRH trifluoroacetate salt |
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| CAS Number | 61012-19-9 | Molecular Weight | 1209.398 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C59H84N16O12 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | lecirelin |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Lecirelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue. Lecirelin is widely used for the research of bovine ovarian follicular cysts[1]. |
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| Related Catalog | Signaling Pathways >>GPCR/G Protein >>GNRH ReceptorResearch Areas >>CancerResearch Areas >>Endocrinology |
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| In Vitro | Lecirelin (2.07 μM) significantly increases the tension and frequency of contractions in preovulatory follicles (PF), small follicular cysts (FC-S), and large follicular cysts (FC-L)[1]. Lecirelin increases the strips from preovulatory follicles contract significantly more than strips from cysts[1]. |
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| References | [1]. Rizzo A et al. Bovine ovarian follicular cysts: in vitro effects of lecirelin, a GnRH analogue. Theriogenology. 2010 Dec;74(9):1559-69. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Molecular Formula | C59H84N16O12 |
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| Molecular Weight | 1209.398 |
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| Exact Mass | 1208.645508 |
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| PSA | 429.04000 |
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| LogP | 0.23 |
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| Index of Refraction | 1.678 |
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| InChIKey | XJWIEWPGHRSZJM-MGZASHDBSA-N |
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| SMILES | CCNC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc1cnc[nH]1)NC(=O)C1CCC(=O)N1)C(C)(C)C |
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| Storage condition | -20°C |
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Synonyms
| Lecirelin (Dalmarelin) Acetate |
| 5-Oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-methyl-D-valyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide |
| L-Prolinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-3-methyl-D-valyl-L-leucyl-L-arginyl-N-ethyl- |
| Lecirelin Acetate |
| Supergestran |
| GLP-HIS-TRP-SER-TYR-TLE-LEU-ARG-PRO-NHET |
