CAS 134678-17-4|Lamivudine
| Common Name | Lamivudine | ||
|---|---|---|---|
| CAS Number | 134678-17-4 | Molecular Weight | 229.256 |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 475.4±55.0 °C at 760 mmHg |
| Molecular Formula | C8H11N3O3S | Melting Point | 177 °C |
| MSDS | ChineseUSA | Flash Point | 241.3±31.5 °C |
| Symbol | GHS08 | Signal Word | Warning |
Names
| Name | lamivudine |
|---|---|
| Synonym | More Synonyms |
Lamivudine BiologicalActivity
| Description | Lamivudine is a nucleoside reverse transcriptase inhibitors?(NRTIs). Lamivudine can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>HIVSignaling Pathways >>Anti-infection >>Reverse TranscriptaseResearch Areas >>Infection |
| References | [1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551. [2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4. |
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 475.4±55.0 °C at 760 mmHg |
| Melting Point | 177 °C |
| Molecular Formula | C8H11N3O3S |
| Molecular Weight | 229.256 |
| Flash Point | 241.3±31.5 °C |
| Exact Mass | 229.052109 |
| PSA | 115.67000 |
| LogP | -0.71 |
| Vapour Pressure | 0.0±2.7 mmHg at 25°C |
| Index of Refraction | 1.755 |
| InChIKey | JTEGQNOMFQHVDC-NKWVEPMBSA-N |
| SMILES | Nc1ccn(C2CSC(CO)O2)c(=O)n1 |
| Storage condition | Freezer |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H361 |
| Precautionary Statements | P281 |
| Hazard Codes | Xi |
| Risk Phrases | 63 |
| RIDADR | NONH for all modes of transport |
| RTECS | UW7361333 |
| HS Code | 2934999090 |
Customs
| HS Code | 2938901000 |
|---|---|
| Summary | HS: 2938901000. 4-amino-1-((2r,5s)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1h)-one. VAT:17.0%. tax rebate rate:13.0%. supervision conditions:None. MFN tarrif:6.5%. general tariff:20.0% |
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Synonyms
| 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]- |
| 3TC |
| Heptodin |
| cent |
| (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine |
| Lamivudine |
| Zeffix |
| Zefix |
| Hepitec |
| Heptivir |
| 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) |
| 2',3'-Dideoxy-3'-thiacytidine |
| Heptovir |
| 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one |
| MFCD00869739 |
| (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cystosine |
| 4-Amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone |
| Epivir |
| 4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one |
| 3&L-SddC |
