CAS 617-35-6|Ethylpyruvate
| Common Name | Ethylpyruvate | ||
|---|---|---|---|
| CAS Number | 617-35-6 | Molecular Weight | 116.115 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 155.0±0.0 °C at 760 mmHg |
| Molecular Formula | C5H8O3 | Melting Point | -58 °C |
| MSDS | ChineseUSA | Flash Point | 45 ºC |
| Symbol | GHS02 | Signal Word | Warning |
Names
| Name | Ethyl pyruvate |
|---|---|
| Synonym | More Synonyms |
Ethylpyruvate BiologicalActivity
| Description | Ethyl pyruvate is a simple derivative of the endogenous metabolite, pyruvic acid. Ethyl pyruvate is an anti-inflammatory agent[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Fink MP. Ethyl pyruvate: a novel anti-inflammatory agent. J Intern Med. 2007 Apr;261(4):349-62. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 155.0±0.0 °C at 760 mmHg |
| Melting Point | -58 °C |
| Molecular Formula | C5H8O3 |
| Molecular Weight | 116.115 |
| Flash Point | 45 ºC |
| Exact Mass | 116.047340 |
| PSA | 43.37000 |
| LogP | 0.05 |
| Vapour Pressure | 3.1±0.2 mmHg at 25°C |
| Index of Refraction | 1.399 |
| InChIKey | XXRCUYVCPSWGCC-UHFFFAOYSA-N |
| SMILES | CCOC(=O)C(C)=O |
| Storage condition | 0-6°C |
Safety Information
| Symbol | GHS02 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi,F |
| Risk Phrases | R10 |
| Safety Phrases | S16 |
| RIDADR | UN 3272 3/PG 3 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 3 |
| HS Code | 2918300090 |
Customs
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Articles46
More Articles| Effects of ethyl pyruvate on leukocyte-endothelial interactions in the mesenteric microcirculation during early sepsis treatment. Clinics (Sao. Paulo.) 70 , 508-14, (2015) Experimental studies on sepsis have demonstrated that ethyl pyruvate is endowed with antioxidant and anti-inflammatory properties. This study aimed to investigate the effects of ethyl pyruvate on leuk... | |
| HMGB1 enhances immune suppression by facilitating the differentiation and suppressive activity of myeloid-derived suppressor cells. Cancer Res. 74(20) , 5723-33, (2014) Chronic inflammation often precedes malignant transformation and later drives tumor progression. Likewise, subversion of the immune system plays a role in tumor progression, with tumoral immune escape... | |
| Ethyl pyruvate significantly inhibits tumour necrosis factor-α, interleukin-1β and high mobility group box 1 releasing and attenuates sodium taurocholate-induced severe acute pancreatitis associated with acute lung injury. Clin. Exp. Immunol. 172(3) , 417-26, (2013) In this study, we examined the effect of ethyl pyruvate (EP) on pulmonary inflammation in rats with severe pancreatitis-associated acute lung injury (ALI). Severe acute pancreatitis (SAP) was induced ... |
Synonyms
| MFCD00009123 |
| ethyl 2-oxopropanoate |
| EINECS 210-511-2 |
| Ethylpyruvate |
