CAS 13832-70-7|Stearyl glycyrrhetinate

Introduction:Basic information about CAS 13832-70-7|Stearyl glycyrrhetinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameStearyl glycyrrhetinate
CAS Number13832-70-7Molecular Weight723.162
Density1.0±0.1 g/cm3Boiling Point732.5±60.0 °C at 760 mmHg
Molecular FormulaC48H82O4Melting Point70-77ºC
MSDS/Flash Point198.8±26.4 °C

Names

Nameoctadecyl (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
SynonymMore Synonyms

Stearyl glycyrrhetinate BiologicalActivity

DescriptionStearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects[1].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
In VitroGlycyrrhetinic acid (GRA) and disodium succinoyl glycyrrhetinate (GR-SU) shows strong antibacterial activities compared to the other three agents tested. At a higher concentration (above 2x MIC), GRA and GR-SU shows bactericidal activity, whereas at a concentration of 1x MIC, they showed a bacteriostatic effect[1].
References

[1]. Oyama K, et al. Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus. PLoS One. 2016 Nov 7;11(11):e0165831.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point732.5±60.0 °C at 760 mmHg
Melting Point70-77ºC
Molecular FormulaC48H82O4
Molecular Weight723.162
Flash Point198.8±26.4 °C
Exact Mass722.621338
PSA63.60000
LogP16.03
Vapour Pressure0.0±5.4 mmHg at 25°C
Index of Refraction1.525
InChIKeyWNIFXKPDILJURQ-JKPOUOEOSA-N
SMILESCCCCCCCCCCCCCCCCCCOC(=O)C1(C)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1

Safety Information

HS Code2918990090

Customs

HS Code2918990090
Summary2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

Olean-12-en-30-oic acid, 3-hydroxy-11-oxo-, octadecyl ester, (3β,5ξ,18α)-
Stearyl glycyrrhetinate
a-Glycyrrhetinic acid stearyl ester
Octadecyl glycyrrhetinate
Olean-12-en-30-oicacid,3b-hydroxy-11-oxo-,octadecyl ester(8CI)
stearyl glycyrrhizinate
n-Octadecyl glycyrrhetinate
Olean-12-en-30-oic acid, 3-hydroxy-11-oxo-, octadecyl ester, (3β)-
stearyl glycyrrhizate
stearyl glycyrrhetate
Octadecyl (3β)-3-hydroxy-11-oxoolean-12-en-30-oate
CO-Grhetinol
Octadecyl (3β,5ξ,18α)-3-hydroxy-11-oxoolean-12-en-30-oate
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