CAS 13951-70-7|16α-Hydroxyprednisolone

Introduction：Basic information about CAS 13951-70-7|16α-Hydroxyprednisolone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 16α-Hydroxyprednisolone BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	16α-Hydroxyprednisolone
CAS Number	13951-70-7	Molecular Weight	376.443
Density	1.4±0.1 g/cm3	Boiling Point	591.5±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₈O₆	Melting Point	235-238ºC
MSDS	/	Flash Point	325.6±26.6 °C

Names

Name	16a-Hydroxyprednisolone
Synonym	More Synonyms

16α-Hydroxyprednisolone BiologicalActivity

Description	16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes[1][2].
Related Catalog	Research Areas >>Inflammation/Immunology
References	[1]. Xavier Matabosch, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404(2):325-40. [2]. G Jönsson, et al. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos. 1995 Jan;23(1):137-42.

Description

16α-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide via cytochrome P450 3A (CYP3A) enzymes[1][2].

Related Catalog

Research Areas >>Inflammation/Immunology

References

[1]. Xavier Matabosch, et al. Identification of budesonide metabolites in human urine after oral administration. Anal Bioanal Chem. 2012 Aug;404(2):325-40.

[2]. G Jönsson, et al. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. Drug Metab Dispos. 1995 Jan;23(1):137-42.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	591.5±50.0 °C at 760 mmHg
Melting Point	235-238ºC
Molecular Formula	C₂₁H₂₈O₆
Molecular Weight	376.443
Flash Point	325.6±26.6 °C
Exact Mass	376.188599
PSA	115.06000
LogP	0.95
Vapour Pressure	0.0±3.8 mmHg at 25°C
Index of Refraction	1.630
InChIKey	SEKYBDYVXDAYPY-ILNISADRSA-N
SMILES	CC12C=CC(=O)C=C1CCC1C2C(O)CC2(C)C1CC(O)C2(O)C(=O)CO
Storage condition	-20°C Freezer

Safety Information

HS Code	2937210000

Customs

HS Code	2914400090
Summary	2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Synonyms

MFCD00872019

(11β,16α)-11,16,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione

11β,16α,17α,21-Tetrahydroxypregna-1,4-diene-3,20-dione

Pregna-1,4-diene-3,20-dione, 11,16,17,21-tetrahydroxy-, (11β,16α)-

EINECS 237-731-1

11a,16b,17,21-Tetrahydroxy-pregna-1,4-diene-3,20-dione

Budesonide Impurity 1

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