CAS 13457-18-6|Afugan
| Common Name | Afugan | ||
|---|---|---|---|
| CAS Number | 13457-18-6 | Molecular Weight | 373.365 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | / |
| Molecular Formula | C14H20N3O5PS | Melting Point | 51℃ |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS06, GHS09 | Signal Word | Danger |
Names
| Name | pyrazophos |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Melting Point | 51℃ |
| Molecular Formula | C14H20N3O5PS |
| Molecular Weight | 373.365 |
| Exact Mass | 373.086121 |
| PSA | 126.08000 |
| LogP | 3.01 |
| Index of Refraction | 1.596 |
| InChIKey | JOOMJVFZQRQWKR-UHFFFAOYSA-N |
| SMILES | CCOC(=O)c1cn2nc(OP(=S)(OCC)OCC)cc2nc1C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 218 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year: 23,538,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,734,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 435 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1266,1989
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 118 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,734,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 184 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,1266,1989 *** REVIEWS *** TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 53,99,1974
Safety Information
| Symbol | GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H332-H410 |
| Precautionary Statements | P273-P301 + P310-P501 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn: Harmful;N: Dangerous for the environment; |
| Risk Phrases | 20/22-50/53 |
| Safety Phrases | 36/37-46-60-61 |
| RIDADR | UN 2783 |
| RTECS | TF2035000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
Articles4
More Articles| [Biochemical changes in the myocardium in experimental chronic pirazofos poisoning]. Probl. Khig. 10 , 52-8, (1985) The authors investigate the 12 month effect of the organophosphorus pesticide "Pyrazophos", in the myocardium status of albino male rats treated per os by 1/20, 1/100, and 1/200 LD50 of the preparatio... | |
| Removal of pyrazophos from treated fabric using household laundering. Bull. Environ. Contam. Toxicol. 42(5) , 687-90, (1989) | |
| Pesticide residues in artichokes: effect of different head shape. J. Environ. Sci. Health B 31(6) , 1189-99, (1996) Residues of three pesticides (dimethoate, parathion, and pyrazophos) in two artichoke cultivars, Masedu and Spinoso sardo, were investigated. The amount of pesticides in artichokes was greatly affecte... |
Synonyms
| 2-(Diethoxy-thiophosphoryloxy)-5-methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid ethyl ester |
| Ethyl 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate |
| ethyl 2-diethoxyphosphinothioyloxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate |
| Pyrazolo[1,5-a]pyrimidine-6-carboxylic acid, 2-[(diethoxyphosphinothioyl)oxy]-5-methyl-, ethyl ester |
| ethyl 2-[(diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate |
| 2-Hydroxy-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic Acid Ethyl Ester O-Ester with O,O-Diethyl Phosphorthioate |
| PYRAZOPHOS |
| EINECS 236-656-1 |
| Curamil |
| MFCD00055494 |
| O-6-ethoxycarbonyl-5-methylpyrazolo[1,5-a]pyrimidin-2-yl O,O-diethyl phosphorothioate |
| Afugan |
| 2-[(Diethoxyphosphinothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic Acid Ethyl Ester |
