Introduction：Basic information about CAS 475115-35-6|Galnon, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Galnon |
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| CAS Number | 475115-35-6 | Molecular Weight | 678.82 |
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| Density | 1.242g/cm3 | Boiling Point | 937.5ºC at 760 mmHg |
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| Molecular Formula | C40H46N4O6 | Melting Point | / |
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| MSDS | / | Flash Point | 520.8ºC |
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Names
| Name | Galnon,3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide |
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| Synonym | More Synonyms |
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Galnon BiologicalActivity
| Description | Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2]. |
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| Related Catalog | Research Areas >>Neurological DiseaseSignaling Pathways >>GPCR/G Protein >>Neuropeptide Y Receptor |
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| References | [1]. Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5. [2]. Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20. |
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Chemical & Physical Properties
| Density | 1.242g/cm3 |
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| Boiling Point | 937.5ºC at 760 mmHg |
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| Molecular Formula | C40H46N4O6 |
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| Molecular Weight | 678.82 |
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| Flash Point | 520.8ºC |
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| Exact Mass | 678.34200 |
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| PSA | 152.76000 |
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| LogP | 8.08650 |
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| Index of Refraction | 1.613 |
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| InChIKey | IKNOZZKXIDSTRN-PXLJZGITSA-N |
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| SMILES | Cc1cc(=O)oc2cc(NC(=O)C(CCCCN)NC(=O)C(CC3CCCCC3)NC(=O)OCC3c4ccccc4-c4ccccc43)ccc12 |
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Safety Information
Synonyms
| GALNON |
| FMoc-b-cyclohexyl-Ala-Lys-AMC |
| VU 590 dihydrochloride |
| FMoc-Cha-Lys-AMC |
