Introduction：Basic information about CAS 61630-32-8|4-Androsten-4-ol-3,17-dione acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 4-Androsten-4-ol-3,17-dione acetate |
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| CAS Number | 61630-32-8 | Molecular Weight | 344.44500 |
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| Density | 1.18g/cm3 | Boiling Point | 501.2ºC at 760 mmHg |
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| Molecular Formula | C21H28O4 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 219.2ºC |
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Names
| Name | 4-Androsten-4-ol-3,17-dione acetate |
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| Synonym | More Synonyms |
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Chemical & Physical Properties
| Density | 1.18g/cm3 |
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| Boiling Point | 501.2ºC at 760 mmHg |
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| Molecular Formula | C21H28O4 |
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| Molecular Weight | 344.44500 |
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| Flash Point | 219.2ºC |
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| Exact Mass | 344.19900 |
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| PSA | 60.44000 |
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| LogP | 3.97820 |
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| Index of Refraction | 1.548 |
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| InChIKey | LRXSFNGKRCOHRS-VMRCMBGLSA-N |
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| SMILES | CC(=O)OC1=C2CCC3C4CCC(=O)C4(C)CCC3C2(C)CCC1=O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- BV8153000
- CHEMICAL NAME :
- Androst-4-ene-3,17-dione, 4-hydroxy-, acetate (ester)
- CAS REGISTRY NUMBER :
- 61630-32-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H28-O4
- MOLECULAR WEIGHT :
- 344.49
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- DOSE :
- 300 mg/kg
- SEX/DURATION :
- female 2-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 18,365,1978
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- DOSE :
- 375 mg/kg
- SEX/DURATION :
- female 18 day(s) pre-mating female 1-8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - mating performance (e.g. # sperm positive females per # females mated; # copulations per # estrus cycles)
- REFERENCE :
- BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 18,365,1978
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| RTECS | BV8153000 |
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Articles14
More Articles
| Aromatase inhibitors and the treatment of breast cancer. J. Steroid Biochem. 24 , 91, (1986) Inhibition of aromatase to reduce estrogen production by peripheral and ovarian tissue could be a useful approach to treating hormone-dependent breast cancer. Several C19, 17 keto steroids have been i... | |
| Inhibition of estrogen biosynthesis and regression of mammary tumors by aromatase inhibitors. Adv. Exp. Med. Biol. 138 , 179-90, (1981)
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| Overview of recent development of aromatase inhibitors. Cancer Res. 42(8 Suppl) , 3312s-3314s, (1982) Since the first publication in 1973 concerning aromatase inhibitors, several effective compounds have been reported by a number of investigators. Our studies with 4-hydroxyandrostene-3,17-dione, 4-ace... | |
Synonyms
| [(8R,9S,10R,13S,14S)-10,13-dimethyl-3,17-dioxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-4-yl] acetate |
