CAS 135702-23-7|Diabetes Associated Peptide Fragment 8-37 Amide

Introduction：Basic information about CAS 135702-23-7|Diabetes Associated Peptide Fragment 8-37 Amide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	Diabetes Associated Peptide Fragment 8-37 Amide
CAS Number	135702-23-7	Molecular Weight	3183.45000
Density	/	Boiling Point	/
Molecular Formula	C₁₃₈H₂₁₆N₄₂O₄₅	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Human amylin 8-37
Synonym	More Synonyms

BiologicalActivity

Description	Amylin (8-37), human is a fragment of human Amylin. Amylin (8-37), human can direct vasodilator effects in the isolated mesenteric resistance artery of the rat. Human Amylin is a small hormone secreted by pancreatic β-cells that forms aggregates under insulin deficiency metabolic conditions, and it constitutes a pathological hallmark of type II diabetes mellitus[1].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
References	[1]. H C Champion, et al. Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat. Peptides. 2001 Sep;22(9):1427-34.

Chemical & Physical Properties

Molecular Formula	C₁₃₈H₂₁₆N₄₂O₄₅
Molecular Weight	3183.45000
Exact Mass	3181.59000
PSA	1444.20000
InChIKey	OBFZUAVBRVNJDZ-AWNVCVQVSA-N
SMILES	CCC(C)C(NC(=O)C(C)NC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(N)=O)NC(=O)C(NC(=O)C(C)N)C(C)O)C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NCC(=O)NC(CO)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(Cc1ccc(O)cc1)C(N)=O)C(C)O)C(C)C)C(C)O
Storage condition	−20°C

Safety Information

WGK Germany	3
HS Code	3505100000

Customs

HS Code	3505100000

Synonyms

L-Alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-asparaginyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-seryl-L-asparaginyl-L-asparaginyl-L-phenylalanylglycyl-L-alanyl-L-isoleucyl-L-leucyl-L-seryl-L-seryl-L-threonyl-L-asparaginyl-L-valylglycyl-L-seryl-L-asparaginyl-L-threonyl-L-tyrosinamide

MFCD00214583

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