Introduction：Basic information about CAS 251647-48-0|5'-O-DMT-2'-O-MOE-N6-Bz-rA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5'-O-DMT-2'-O-MOE-N6-Bz-rA |
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| CAS Number | 251647-48-0 | Molecular Weight | 731.79 |
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| Density | 1.31 | Boiling Point | / |
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| Molecular Formula | C41H41N5O8 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]purin-6-yl]benzamide |
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| Synonym | More Synonyms |
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5'-O-DMT-2'-O-MOE-N6-Bz-rA BiologicalActivity
| Description | N-Benzoyl-5'-O-dmtr-2'-O-(2-methoxyethyl)-adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. |
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Chemical & Physical Properties
| Density | 1.31 |
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| Molecular Formula | C41H41N5O8 |
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| Molecular Weight | 731.79 |
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| Exact Mass | 731.29600 |
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| PSA | 151.80000 |
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| LogP | 5.77840 |
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| InChIKey | KEVMXGNDTKPSMC-MUMPVVMASA-N |
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| SMILES | COCCOC1C(O)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC1n1cnc2c(NC(=O)c3ccccc3)ncnc21 |
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| Storage condition | 2-8°C |
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Synonyms
| N-Benzoyl-5'-O-DMTr-2'-O-(2-methoxyethyl)adenosine |
| 5'-O-DMT-2'-O-MOE-N6-Bz-rA |
