CAS 138-89-6|N,N-Dimethyl-4-nitrosoaniline

Introduction：Basic information about CAS 138-89-6|N,N-Dimethyl-4-nitrosoaniline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Articles30
7. Synonyms

Common Name	N,N-Dimethyl-4-nitrosoaniline
CAS Number	138-89-6	Molecular Weight	150.178
Density	1.0±0.1 g/cm3	Boiling Point	258.7±23.0 °C at 760 mmHg
Molecular Formula	C₈H₁₀N₂O	Melting Point	85-87 °C(lit.)
MSDS	ChineseUSA	Flash Point	110.3±22.6 °C
Symbol	GHS02, GHS06	Signal Word	Danger

Names

Name	N,N-dimethyl-4-nitrosoaniline
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.0±0.1 g/cm3
Boiling Point	258.7±23.0 °C at 760 mmHg
Melting Point	85-87 °C(lit.)
Molecular Formula	C₈H₁₀N₂O
Molecular Weight	150.178
Flash Point	110.3±22.6 °C
Exact Mass	150.079315
PSA	32.67000
LogP	2.02
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.529
InChIKey	CMEWLCATCRTSGF-UHFFFAOYSA-N
SMILES	CN(C)c1ccc(N=O)cc1
Stability	Stable. Incompatible with strong oxidizing agents, strong reducing agents, strong acids, acetic acid, acetic anhydride. Highly flammable (?)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX7175000

CHEMICAL NAME :: Aniline, N,N-dimethyl-p-nitroso-

CAS REGISTRY NUMBER :: 138-89-6

BEILSTEIN REFERENCE NO. :: 0607293

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C8-H10-N2-O

MOLECULAR WEIGHT :: 150.20

WISWESSER LINE NOTATION :: ONR DN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 650 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7300 mg/kg/1Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Blood - lymphoma, including Hodgkin's disease

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986

Safety Information

Symbol	GHS02, GHS06
Signal Word	Danger
Hazard Statements	H251-H301-H315-H317-H319-H335
Precautionary Statements	P235 + P410-P261-P280-P301 + P310-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	F:Highlyflammable;T:Toxic;
Risk Phrases	R23/24/25;R33;R8
Safety Phrases	S16-S26-S36/37-S45
RIDADR	UN 1369 4.2/PG 2
WGK Germany	3
RTECS	BX7175000
Packaging Group	II
Hazard Class	4.2
HS Code	2921430090

Customs

HS Code	2921430090
Summary	HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles30

Role of type I & type II radicals in DNA damage and activation of Caspase 3 via mitochondrial pathway induced by photosensitized benzophenone

Toxicol. Lett. 235(2) , 84-95, (2015)

[Display omitted]

Non-animal photosafety screening for complex cosmetic ingredients with photochemical and photobiochemical assessment tools.

Regul Toxicol Pharmacol 72 , 578-85, (2015)

Previously, a non-animal screening approach was proposed for evaluating photosafety of cosmetic ingredients by means of in vitro photochemical and photobiochemical assays; however, complex cosmetic in...

Phototoxic Risk Assessments on Benzophenone Derivatives: Photobiochemical Assessments and Dermal Cassette-Dosing Pharmacokinetic Study.

J. Pharmacol. Exp. Ther. 354 , 195-202, (2015)

This study aimed to qualify photosafety screening on the basis of photochemical and pharmacokinetic (PK) data on dermally applied chemicals. Six benzophenone derivatives (BZPs) were selected as model ...

Synonyms

EINECS 205-343-1

p-nitrosodimethyl aniline

p-dimethylaminonitrosobenzene

p-Nitrosodimethylanilide

4-nitroso-N,N-di-methylaniline

MFCD00002063

N,N-dimethyl-p-nitrosoaniline

Paranitrosodimethylanilide

Benzenamine, N,N-dimethyl-4-nitroso-

p-Nitroso-N,N-dimethylaniline

N,N-Dimethyl-4-nitrosoaniline

4-Nitrosodimethylaniline

Accelerine

4-Nitroso-N,N-dimethylaniline

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