CAS 1637-39-4|trans-Zeatin

Introduction：Basic information about CAS 1637-39-4|trans-Zeatin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. trans-Zeatin BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Articles32
7. Synonyms

Common Name	trans-Zeatin
CAS Number	1637-39-4	Molecular Weight	219.243
Density	1.4±0.1 g/cm3	Boiling Point	395.0±52.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₃N₅O	Melting Point	207 °C
MSDS	ChineseUSA	Flash Point	192.7±30.7 °C

Names

Name	trans-zeatin
Synonym	More Synonyms

trans-Zeatin BiologicalActivity

Description	trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
Related Catalog	Research Areas >>OthersNatural Products >>Others
Target	MEK ERK
In Vitro	trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division[1]. trans-Zeatin (20, 40 or 80 μM) inhibits UV-induced MEK/ERK activation, upregulates AQP3 in a time- and dose-dependent manner, and attenuates UV induced loss of AQP3 in keratinocytes (HaCaT cells). UV-induced AQP3 downregulation is blocked by MEK/ERK inhibitors. Trans-Zeatin (80 μM) attenuates UV-induced downregulation of wound healing and water permeability in HaCaT cells[2].
References	[1]. Li Q, et al. Endogenous trans-zeatin content in plants with different metal-accumulating ability: a field survey. Environ Sci Pollut Res Int. 2016 Dec;23(23):23422-23435. Epub 2016 Sep 9. [2]. Ji C, et al. Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes. Int J Mol Med. 2010 Aug;26(2):257-63.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	395.0±52.0 °C at 760 mmHg
Melting Point	207 °C
Molecular Formula	C₁₀H₁₃N₅O
Molecular Weight	219.243
Flash Point	192.7±30.7 °C
Exact Mass	219.112015
PSA	86.72000
LogP	-1.02
Vapour Pressure	0.0±2.1 mmHg at 25°C
Index of Refraction	1.684
InChIKey	UZKQTCBAMSWPJD-FARCUNLSSA-N
SMILES	CC(=CCNc1ncnc2nc[nH]c12)CO
Storage condition	−20°C
Water Solubility	H2O: soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EM9506000

CHEMICAL NAME :: 2-Buten-1-ol, 2-methyl-4-(purin-6-ylamino)-, (E)-

CAS REGISTRY NUMBER :: 1637-39-4

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C10-H13-N5-O

MOLECULAR WEIGHT :: 219.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Leukocyte

DOSE/DURATION :: 100 umol/L

REFERENCE :: EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 32,29,1976

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	EM9506000

Articles32

Silicon induces resistance to the brown spot fungus Cochliobolus miyabeanus by preventing the pathogen from hijacking the rice ethylene pathway.

New Phytol. 206(2) , 761-73, (2015)

Although numerous studies have shown the ability of silicon (Si) to mitigate a wide variety of abiotic and biotic stresses, relatively little is known about the underlying mechanism(s). Here, we have ...

High-internal-phase-emulsion polymeric monolith coupled with liquid chromatography-electrospray tandem mass spectrometry for enrichment and sensitive detection of trace cytokinins in plant samples.

Anal. Bioanal. Chem 407 , 6071-9, (2015)

High-internal-phase-emulsion polymers (polyHIPEs) show great promise as solid-phase-extraction (SPE) materials because of the tremendous porosity and highly interconnected framework afforded by the hi...

Physiological response to drought in radiata pine: phytohormone implication at leaf level.

Tree Physiol. 32(4) , 435-49, (2012)

Pinus radiata D. Don is one of the most abundant species in the north of Spain. Knowledge of drought response mechanisms is essential to guarantee plantation survival under reduced water supply as pre...

Synonyms

(2z)-2-methyl-4-(9h-purin-6-ylamino)but-2-en-1-ol

2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (2E)-

cis-zeatin

trans-Zeatin (synthetic)

(2E)-2-Methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol

2-Buten-1-ol, 2-methyl-4-(3H-purin-6-ylamino)-, (2Z)-

(E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol

oxyenadenine

(2E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol

ZEATIN TRANS ISOMER

(2Z)-2-Methyl-4-(3H-purin-6-ylamino)-2-buten-1-ol

2-Buten-1-ol, 2-methyl-4-(3H-purin-6-ylamino)-, (2E)-

6-(4-Hydroxy-3-methyl-2-butenylamino)purine

(E)-zeatin

(2E)-2-Methyl-4-(3H-purin-6-ylamino)-2-buten-1-ol

MFCD00213654

(2E)-2-Methyl-4-(1H-purin-6-ylamino)but-2-en-1-ol

trans-Zeatin

(2E)-2-Methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol

2-Buten-1-ol, 2-methyl-4-(purin-6-ylamino)-, (E)-

N6-(4-Hydroxy-3-methyl-2-buten-1-yl)adenine

Zeatin

6-(4-Hydroxy-3-methylbut-2-enylamino)purine (N6-(4-Hydroxy-3-methyl-2-buten-1-yl)adenine

Zeatine

(2Z)-2-Methyl-4-(1H-purin-6-ylamino)-2-buten-1-ol

TRANS ISOMER-ZEATIN

ZEATINRESEARCH GRADE

2-Buten-1-ol, 2-methyl-4-(7H-purin-6-ylamino)-, (2Z)-

6-(4-Hydroxy-3-methylbut-2-enylamino)purine

2-Buten-1-ol, 2-methyl-4-(1H-purin-6-ylamino)-, (E)-

ZEATIN,CRYSTALLIZED

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