CAS 160391-70-8|TYRPHOSTIN AG 1290

Introduction:Basic information about CAS 160391-70-8|TYRPHOSTIN AG 1290, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTYRPHOSTIN AG 1290
CAS Number160391-70-8Molecular Weight250.164
Density1.7±0.1 g/cm3Boiling Point478.9±45.0 °C at 760 mmHg
Molecular FormulaC10H6N2O6Melting Point/
MSDS/Flash Point243.4±28.7 °C

Names

Name(E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoic acid
SynonymMore Synonyms

TYRPHOSTIN AG 1290 BiologicalActivity

DescriptionEntacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo[1].
Related CatalogResearch Areas >>Metabolic DiseaseSignaling Pathways >>Protein Tyrosine Kinase/RTK >>c-Met/HGFR
Target

Tyrosine kinase[1]

References

[1]. Nakagohri T, et al. The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury. Surg Today. 1998;28(5):517-21.  

Chemical & Physical Properties

Density1.7±0.1 g/cm3
Boiling Point478.9±45.0 °C at 760 mmHg
Molecular FormulaC10H6N2O6
Molecular Weight250.164
Flash Point243.4±28.7 °C
Exact Mass250.022583
PSA147.37000
LogP2.19
Vapour Pressure0.0±1.3 mmHg at 25°C
Index of Refraction1.750
InChIKeyXDDDOLQEZBJWFZ-LZCJLJQNSA-N
SMILESN#CC(=Cc1cc(O)c(O)c([N+](=O)[O-])c1)C(=O)O

Synonyms

unii-3u917c92qr
(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylic acid
ss-3041
2-Propenoic acid, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-, (2E)-
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