Introduction:Basic information about CAS 160391-70-8|TYRPHOSTIN AG 1290, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | TYRPHOSTIN AG 1290 |
|---|
| CAS Number | 160391-70-8 | Molecular Weight | 250.164 |
|---|
| Density | 1.7±0.1 g/cm3 | Boiling Point | 478.9±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C10H6N2O6 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 243.4±28.7 °C |
|---|
Names
| Name | (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)prop-2-enoic acid |
|---|
| Synonym | More Synonyms |
|---|
TYRPHOSTIN AG 1290 BiologicalActivity
| Description | Entacapone acid (Tyrphostin AG1290) is a tyrosine kinase inhibitor. Entacapone acid reduces hepatic protein synthesis rate (HPS) in vivo[1]. |
|---|
| Related Catalog | Research Areas >>Metabolic DiseaseSignaling Pathways >>Protein Tyrosine Kinase/RTK >>c-Met/HGFR |
|---|
| Target | Tyrosine kinase[1] |
|---|
| References | [1]. Nakagohri T, et al. The effects of prostaglandin E1 and tyrosine kinase inhibitors on energy status and protein synthetic ability in hepatic ischemia-reperfusion injury. Surg Today. 1998;28(5):517-21. |
|---|
Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
|---|
| Boiling Point | 478.9±45.0 °C at 760 mmHg |
|---|
| Molecular Formula | C10H6N2O6 |
|---|
| Molecular Weight | 250.164 |
|---|
| Flash Point | 243.4±28.7 °C |
|---|
| Exact Mass | 250.022583 |
|---|
| PSA | 147.37000 |
|---|
| LogP | 2.19 |
|---|
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.750 |
|---|
| InChIKey | XDDDOLQEZBJWFZ-LZCJLJQNSA-N |
|---|
| SMILES | N#CC(=Cc1cc(O)c(O)c([N+](=O)[O-])c1)C(=O)O |
|---|
Synonyms
| unii-3u917c92qr |
| (2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylic acid |
| ss-3041 |
| 2-Propenoic acid, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-, (2E)- |