Introduction：Basic information about CAS 1396841-57-8|RGFP966, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | RGFP966 |
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| CAS Number | 1396841-57-8 | Molecular Weight | 362.40000 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C21H19FN4O | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 2-Propenamide, N-(2-amino-4-fluorophenyl)-3-[1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl]-, (2E) |
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| Synonym | More Synonyms |
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RGFP966 BiologicalActivity
| Description | (E,E)-RGFP966 is a selective and CNS permeable HDAC3 inhibitor that can be used for the research of Huntington’s disease[1]. |
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| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>HDACResearch Areas >>Neurological DiseaseSignaling Pathways >>Epigenetics >>HDAC |
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| Target | HDAC3[1] |
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| References | [1]. Jia H, et al. The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice. PLoS One. 2016 Mar 31;11(3):e0152498. |
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Chemical & Physical Properties
| Molecular Formula | C21H19FN4O |
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| Molecular Weight | 362.40000 |
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| Exact Mass | 362.15400 |
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| PSA | 72.94000 |
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| LogP | 4.62390 |
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| Storage condition | -20°C |
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Synonyms
| 2-Propenamide (N-(2-amino-4-fluorophenyl)-3-[1-[(2E)-3-phenyl-2-propen-1-yl]-1H-pyrazol-4-yl] |
| RGFP966 |
