Introduction：Basic information about CAS 1314241-44-5|UNC669, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | UNC669 |
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| CAS Number | 1314241-44-5 | Molecular Weight | 338.243 |
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| Density | 1.4±0.1 g/cm3 | Boiling Point | 458.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C15H20BrN3O | Melting Point | / |
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| MSDS | / | Flash Point | 230.8±28.7 °C |
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Names
| Name | Methanone, (5-bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]- |
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| Synonym | More Synonyms |
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UNC669 BiologicalActivity
| Description | UNC 669 is a potent antagonist of L3MBTL1(IC50=4.2 uM) and L3MBTL3(IC50=3.1 uM).IC50 value: 4.2 uM/3.1 uM (L3MBTL1/L3MBTL3) [1]Target: L3MBTL1/L3MBTL3 |
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| Related Catalog | Signaling Pathways >>Epigenetics >>Histone MethyltransferaseResearch Areas >>Cancer |
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| References | [1]. James LI, et al. Small-molecule ligands of methyl-lysine binding proteins: optimization of selectivity for L3MBTL3. J Med Chem. 2013 Sep 26;56(18):7358-71. |
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Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 458.0±45.0 °C at 760 mmHg |
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| Molecular Formula | C15H20BrN3O |
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| Molecular Weight | 338.243 |
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| Flash Point | 230.8±28.7 °C |
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| Exact Mass | 337.078979 |
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| PSA | 36.44000 |
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| LogP | 1.53 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.608 |
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| InChIKey | CQERVFFAOOUFEQ-UHFFFAOYSA-N |
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| SMILES | O=C(c1cncc(Br)c1)N1CCC(N2CCCC2)CC1 |
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| Storage condition | -20℃ |
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| Water Solubility | Slightly soluble (6.8 g/L) (25 ºC) |
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Synonyms
| (5-Bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]methanone |
| Methanone, (5-bromo-3-pyridinyl)[4-(1-pyrrolidinyl)-1-piperidinyl]- |
| UNC-669 |
| UNC 669 |
