CAS 36951-72-1|5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphine tetratosylate

Introduction：Basic information about CAS 36951-72-1|5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphine tetratosylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Articles42
6. Synonyms

Common Name	5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphine tetratosylate
CAS Number	36951-72-1	Molecular Weight	1363.60
Density	/	Boiling Point	/
Molecular Formula	C₇₂H₆₆N₈O₁₂S₄	Melting Point	/
MSDS	ChineseUSA	Flash Point	/
Symbol	GHS07	Signal Word	Warning

Names

Name	meso-tetrakis(N-methyl-4-pyridyl)porphine tetrakis(p-toluenesulfonate)
Synonym	More Synonyms

BiologicalActivity

Description	TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand, which inhibits the interaction between G-quadruplexes and IGF-1[1]. TMPyP4 tosylate (TMP 1363) is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines[2].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>G-quadruplexSignaling Pathways >>Cell Cycle/DNA Damage >>Telomerase
Target	G-quadruplex[2] Telomerase[2]
References	[1]. Chen H, et al. Insulin-like growth factor type I selectively binds to G-quadruplex structures. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):31-38. [2]. Fujimori J, et al. Antitumor effects of telomerase inhibitor TMPyP4 in osteosarcoma cell lines. J Orthop Res. 2011 Nov;29(11):1707-11.

Chemical & Physical Properties

Molecular Formula	C₇₂H₆₆N₈O₁₂S₄
Molecular Weight	1363.60
Exact Mass	1362.368286
PSA	334.14000
LogP	10.08380
Storage condition	2-8°C
Water Solubility	water: soluble50MM(lit.)

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	26-36/37
RIDADR	NONH for all modes of transport
WGK Germany	3

Articles42

Platinum nanoparticles on porphyrin functionalized graphene nanosheets as a superior catalyst for methanol electrooxidation.

Nanoscale 6(24) , 14999-15007, (2014)

A novel nanostructured catalyst of platinum nanoparticles supported on 5,10,15,20-tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p-toluenesulfonate) (TMPyP) functionalized graphene (TMPyP-graphene) is ...

"Turn-off-on" fluorescent sensor for (N-methyl-4-pyridyl) porphyrin -DNA and G-quadruplex interactions based on ZnCdSe quantum dots.

Anal. Chim. Acta 888 , 131-7, (2015)

As a new detection model, the reversible fluorescence "turn-off-on" sensor based on quantum dots (QDs) has already been successfully employed in the detections of many biochemical materials, especiall...

The singlet-oxygen-sensitized delayed fluorescence in mammalian cells: a time-resolved microscopy approach.

Photochem. Photobiol. Sci. 14(4) , 700-13, (2015)

The present work provides a proof-of-concept that the singlet oxygen-sensitized delayed fluorescence (SOSDF) can be detected from individual living mammalian cells in a time-resolved microscopy experi...

Synonyms

4,4',4'',4'''-(5,10,15,20-Porphyrintetrayl)tetrakis(1-methylpyridinium) tetrakis(4-methylbenzenesulfonate)

TMPyP4 tosylate

4-methylbenzenesulfonate,5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,22-dihydroporphyrin

4,4',4'',4'''-Porphyrin-5,10,15,20-tetrayltetrakis(1-methylpyridinium) tetrakis(4-methylbenzenesulfonate)

5,10,15,20-Tetrakis(N-methyl-4-pyridyl)porphine tetratosylate

MFCD00013468

TMPyP ,Mg] [Fo

α,β,γ,δ-Tetrakis(1-methylpyridinium-4-yl)porphyrin p-Toluenesulfonate

TMPYP

tmpyp tetratosylate

Recommended......