CAS 135-02-4|o-Anisaldehyde

Introduction：Basic information about CAS 135-02-4|o-Anisaldehyde, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. o-Anisaldehyde BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
5. Safety Information
6. Customs
7. Articles4
8. Synonyms

Common Name	o-Anisaldehyde
CAS Number	135-02-4	Molecular Weight	136.148
Density	1.1±0.1 g/cm3	Boiling Point	243.5±0.0 °C at 760 mmHg
Molecular Formula	C₈H₈O₂	Melting Point	34-40 °C(lit.)
MSDS	ChineseUSA	Flash Point	117.8±0.0 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2-Methoxybenzaldehyde
Synonym	More Synonyms

o-Anisaldehyde BiologicalActivity

Description	2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalSignaling Pathways >>Anti-infection >>Bacterial
References	[1]. Zhaoxiang Huang, et al. Synergistic effects of cinnamaldehyde and cinnamic acid in cinnamon essential oil against S. pullorum. Industrial Crops and Products, 2021-02-03. [2]. Sheikh Shreaz, et al. Interesting anticandidal effects of anisic aldehydes on growth and proton-pumping-ATPase-targeted activity. Microb Pathog. 2011 Oct;51(4):277-84.

Description

2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity[1].

Related Catalog

Research Areas >>InfectionSignaling Pathways >>Anti-infection >>FungalSignaling Pathways >>Anti-infection >>Bacterial

References

[1]. Zhaoxiang Huang, et al. Synergistic effects of cinnamaldehyde and cinnamic acid in cinnamon essential oil against S. pullorum. Industrial Crops and Products, 2021-02-03.

[2]. Sheikh Shreaz, et al. Interesting anticandidal effects of anisic aldehydes on growth and proton-pumping-ATPase-targeted activity. Microb Pathog. 2011 Oct;51(4):277-84.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	243.5±0.0 °C at 760 mmHg
Melting Point	34-40 °C(lit.)
Molecular Formula	C₈H₈O₂
Molecular Weight	136.148
Flash Point	117.8±0.0 °C
Exact Mass	136.052429
PSA	26.30000
LogP	1.72
Vapour Pressure	0.0±0.4 mmHg at 25°C
Index of Refraction	1.547
InChIKey	PKZJLOCLABXVMC-UHFFFAOYSA-N
SMILES	COc1ccccc1C=O
Water Solubility	insoluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ2610000

CHEMICAL NAME :: o-Anisaldehyde

CAS REGISTRY NUMBER :: 135-02-4

BEILSTEIN REFERENCE NO. :: 0606301

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C8-H8-O2

MOLECULAR WEIGHT :: 136.16

WISWESSER LINE NOTATION :: VHR BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 125 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/38
Safety Phrases	S26-S36-S37/39
RIDADR	NONH for all modes of transport
WGK Germany	2
RTECS	BZ2610000
Packaging Group	I; II; III
HS Code	29124900

Customs

HS Code	2912499000
Summary	2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles4

3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Bioorg. Med. Chem. 15 , 2006-15, (2007)

Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-q...

Noncovalent immobilization of ionic-tagged box-Cu(OAc)2 complex and its application in asymmetric Henry reaction.

Chirality 24(12) , 1092-5, (2012)

Immobilized Cu(OAc)(2)-bis(oxazolines) via hydrogen bonding by SBA-15 was applied to asymmetric Henry reaction, and good enantioselectivities were obtained (up to 83% ee) between 2-methoxybenzaldehyde...

Food protective effects of Periploca sepium oil and its active component against stored food mites.

J. Food Prot. 75(1) , 118-22, (2012)

The aim of this study was to examine the acaricidal activity of Periploca sepium oil and its active component against Tyrophagus putrescentiae. Based on its 50% lethal dose (LD(50) ) value, P. sepium ...

Synonyms

Benzaldehyde, 2-methoxy-

Salicylaldehyde Methyl Ether

o-Anisaldehyde

MFCD00003308

EINECS 205-171-7

2-Methoxybenzolcarbaldehyd

2-methoxybenzaldehyde

o-Anisaldehyde,Salicylaldehyde methyl ether

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