CAS 13345-51-2|Prostaglandin B1
| Common Name | Prostaglandin B1 | ||
|---|---|---|---|
| CAS Number | 13345-51-2 | Molecular Weight | 336.47 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 531.4±43.0 °C at 760 mmHg |
| Molecular Formula | C20H32O4 | Melting Point | 69-71°C(lit.) |
| MSDS | ChineseUSA | Flash Point | 289.2±24.7 °C |
Names
| Name | prostaglandin B1 |
|---|---|
| Synonym | More Synonyms |
Prostaglandin B1 BiologicalActivity
| Description | Prostaglandin B1 (PGB1) is a metabolite of Prostaglandin E1 (HY-B0131). Prostaglandin E1 is a prostanoid receptor ligand[1][2]. |
|---|---|
| Related Catalog | Research Areas >>EndocrinologySignaling Pathways >>GPCR/G Protein >>Prostaglandin Receptor |
| References | [1]. Bygdeman M, et, al. The effect of eight new prostaglandins on human myometrium. Acta Physiol Scand. 1967 Apr;69(4):320-6. [2]. Zoutendam PH, et, al. Quantitative determination of prostaglandins A1 and B1 in alprostadil (PGE1) by high-performance liquid chromatography. J Chromatogr. 1984 Jan 20;283:281-7. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 531.4±43.0 °C at 760 mmHg |
| Melting Point | 69-71°C(lit.) |
| Molecular Formula | C20H32O4 |
| Molecular Weight | 336.47 |
| Flash Point | 289.2±24.7 °C |
| Exact Mass | 336.230072 |
| PSA | 74.60000 |
| LogP | 3.56 |
| Appearance of Characters | powder | white to light yellow |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |
| Index of Refraction | 1.549 |
| InChIKey | YBHMPNRDOVPQIN-VSOYFRJCSA-N |
| SMILES | CCCCCC(O)C=CC1=C(CCCCCCC(=O)O)C(=O)CC1 |
| Storage condition | −20°C |
| Water Solubility | acetone: 20 mg/mL, clear, colorless to very faintly yellow |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2918990090 |
Customs
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles24
More Articles| NADP(+)-dependent dehydrogenase activity of carbonyl reductase on glutathionylhydroxynonanal as a new pathway for hydroxynonenal detoxification. Free Radic. Biol. Med. 83 , 66-76, (2015) An NADP(+)-dependent dehydrogenase activity on 3-glutathionyl-4-hydroxynonanal (GSHNE) was purified to electrophoretic homogeneity from a line of human astrocytoma cells (ADF). Proteomic analysis iden... | |
| A novel synthesis of racemic and enantiomeric forms of prostaglandin B1 methyl ester. J. Org. Chem. 65(17) , 5127-30, (2000) 3-(Dimethoxyphosphorylmethyl)cyclopent-2-enone was converted into (+/-)-prostaglandin B1 methyl ester in two steps involving regioselective alkylation at C(2) with methyl 7-iodoheptanoate and subseque... | |
| Prostaglandin B1 can modify the pressor responses to sympathetic nerve stimulation. Res. Commun. Chem. Pathol. Pharmacol. 41(3) , 397-405, (1983) PGB1, a metabolite of PGA1, has the ability to enhance peripheral vascular resistance and elevate blood pressure in animals whose vascular tone is low. The effect is not central in origin and apparent... |
Synonyms
| (13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid |
| Prostaglandin B1 |
| (13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-oic acid PGB1 |
| EINECS 234-237-8 |
| Prosta-8(12),13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)- |
| MFCD00036679 |
