CAS 616-02-4|Citraconic anhydride

Introduction：Basic information about CAS 616-02-4|Citraconic anhydride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles36
7. Synonyms

Common Name	Citraconic anhydride
CAS Number	616-02-4	Molecular Weight	112.08300
Density	1.247 g/mL at 25 °C(lit.)	Boiling Point	213-214 °C(lit.)
Molecular Formula	C₅H₄O₃	Melting Point	6-10 °C(lit.)
MSDS	ChineseUSA	Flash Point	215 °F
Symbol	GHS05, GHS06, GHS08	Signal Word	Danger

Names

Name	Citraconic anhydride
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.247 g/mL at 25 °C(lit.)
Boiling Point	213-214 °C(lit.)
Melting Point	6-10 °C(lit.)
Molecular Formula	C₅H₄O₃
Molecular Weight	112.08300
Flash Point	215 °F
Exact Mass	112.01600
PSA	43.37000
LogP	0.01610
Vapour density	4 (vs air)
Index of Refraction	n20/D 1.471(lit.)
InChIKey	AYKYXWQEBUNJCN-UHFFFAOYSA-N
SMILES	CC1=CC(=O)OC1=O
Storage condition	Store at RT.
Water Solubility	decomposes

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GE6825000

CHEMICAL NAME :: Citraconic anhydride

CAS REGISTRY NUMBER :: 616-02-4

BEILSTEIN REFERENCE NO. :: 0001835

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H4-O3

MOLECULAR WEIGHT :: 112.09

WISWESSER LINE NOTATION :: T5VOVJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 218 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SHELL* Shell Chemical Company. (P.O. Box 4320, Houston, TX 77210)

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 26,269,1944

Safety Information

Symbol	GHS05, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H311-H314-H317-H334-H335
Precautionary Statements	P261-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R24;R34;R42/43
Safety Phrases	S26-S36/37/39-S45-S28A
RIDADR	UN 2810 6.1/PG 3
WGK Germany	3
RTECS	GE6825000
Packaging Group	III
Hazard Class	6.1
HS Code	29171990

Customs

HS Code	2917190090
Summary	2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles36

MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays.

PLoS ONE 9(9) , e106255, (2014)

A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked glycan species in ...

Polymeric micelles with citraconic amide as pH-sensitive bond in backbone for anticancer drug delivery.

Int. J. Pharm. 471(1-2) , 28-36, (2014)

A novel pH-sensitive polymeric micelle was reported. Methoxy poly(ethylene glycol)-b-poly(ϵ-caprolactone) copolymer with citraconic amide as pH-sensitive bond was synthesized (mPEG-pH-PCL). The copoly...

Pre-cultivation of adipose tissue-derived microvascular fragments in porous scaffolds does not improve their in vivo vascularisation potential.

Eur. Cell. Mater. 29 , 190-200; discussion 200-1, (2015)

Adipose tissue-derived microvascular fragments represent promising vascularisation units for implanted tissue constructs. However, their reassembly into functional microvascular networks takes several...

Synonyms

EINECS 210-459-0

3-methylfuran-2,5-dione

MFCD00005522

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