CAS 619-08-9|2-Chloro-4-nitrophenol

Introduction：Basic information about CAS 619-08-9|2-Chloro-4-nitrophenol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Articles7
7. Synonyms

Common Name	2-Chloro-4-nitrophenol
CAS Number	619-08-9	Molecular Weight	173.554
Density	1.6±0.1 g/cm3	Boiling Point	290.6±25.0 °C at 760 mmHg
Molecular Formula	C₆H₄ClNO₃	Melting Point	106 °C
MSDS	ChineseUSA	Flash Point	129.6±23.2 °C
Symbol	GHS07	Signal Word	Warning

Names

Name	2-Chloro-4-nitrophenol
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Boiling Point	290.6±25.0 °C at 760 mmHg
Melting Point	106 °C
Molecular Formula	C₆H₄ClNO₃
Molecular Weight	173.554
Flash Point	129.6±23.2 °C
Exact Mass	172.987976
PSA	66.05000
LogP	2.22
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.627
InChIKey	BOFRXDMCQRTGII-UHFFFAOYSA-N
SMILES	O=[N+]([O-])c1ccc(O)c(Cl)c1
Water Solubility	slightly soluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SK5075000

CHEMICAL NAME :: Phenol, 2-chloro-4-nitro-

CAS REGISTRY NUMBER :: 619-08-9

BEILSTEIN REFERENCE NO. :: 2046372

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H4-Cl-N-O3

MOLECULAR WEIGHT :: 173.56

WISWESSER LINE NOTATION :: WNR DQ CG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 900 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - hypermotility, diarrhea

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570573

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal) Skin and Appendages - dermatitis, other (after systemic exposure)

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0570573

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H315-H319-H332-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	2811
WGK Germany	3
RTECS	SK5075000
HS Code	29089000

Customs

HS Code	2908999090
Summary	2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles7

Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors.

Eur. J. Med. Chem. 94 , 175-94, (2015)

An approach for optimization of epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors using truncated thienopyrimidine structures combined with enzymatic assay has been evaluated. This...

Alpha-amylase reactivity in relation to psychopathic traits in adults.

Psychoneuroendocrinology 54 , 14-23, (2015)

Recent investigations of the psychobiology of stress in antisocial youth have benefited from a multi-system measurement model. The inclusion of salivary alpha-amylase (sAA), a surrogate marker of auto...

[Combination of antimycotic preparations and natural proteinase inhibitors in otomycosis].

Rev. Laryngol. Otol. Rhinol. (Bord.) 114(1) , 59-61, (1993)

In vitro experiments, Terrilytinum* increases the antimycotic activity of Clotrimazolum* and Nitrofungin*, and cancels out the inhibitory effect of Contrycal*. The combined application of Clotrimazolu...

Synonyms

2-Chloro-4-nitrophenol

Phenol, 2-chloro-4-nitro-

3-Carboxybenzaldehyde

EINECS 210-578-8

MFCD00043910

2-Chlor-4-nitrobenzolol

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