Introduction：Basic information about CAS 71251-02-0|Octenidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Octenidine |
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| CAS Number | 71251-02-0 | Molecular Weight | 550.90400 |
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| Density | 0.94 g/cm3 | Boiling Point | 609.3ºC at 760 mmHg |
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| Molecular Formula | C36H62N4 | Melting Point | 215-217ºC |
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| MSDS | / | Flash Point | / |
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Names
| Name | Octenidine |
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| Synonym | More Synonyms |
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Octenidine BiologicalActivity
| Description | Octenidine is a potent antibacterial agent, possessing activity against multidrug-resistant Gram-negative pathogens. Octenidine can inhibit the expression of biofilm genes and destroy the formation of biofilms[1][3]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | Octenidine has antimicrobial activity against multidrug-resistant Gram-negative pathogens[1]. Escherichia coli Pseudomonas aeruginosa WT CTX-M-1 CTX-M-15 NDM-1 VIM-15 WT PER-1 VEB-1 OprD VIM-2 MIC (mg/L) 0.5 2.5 1.2 5 2.5 10 40 40 40 40 Octenidine (0-20 h) retardants P. aeruginosa growth in prolonged exposure condition[2]. |
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| In Vivo | Octenidine reduces bacterial counts on mice wounds and inhibit meticillin-resistant Staphylococcus aureus (MRSA)[3]. Animal Model: Mice (a six-millimetre punch full-thickness wound was inoculated with MRSA suspension)[3] Dosage: Administration: Administrated once 24 hours post-wounding Result: Accelerated healing and reduced by >3.6 log cfu/g bacterial counts on the wounds relative to the PBS-treated control. Exhibited lower burden of the inflammatory cells, more mature collagen fibres and well-defined epithelialisation. Inhibited the expression of MRSA and its biofilm genes by nearly 100%. |
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Chemical & Physical Properties
| Density | 0.94 g/cm3 |
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| Boiling Point | 609.3ºC at 760 mmHg |
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| Melting Point | 215-217ºC |
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| Molecular Formula | C36H62N4 |
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| Molecular Weight | 550.90400 |
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| Exact Mass | 550.49700 |
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| PSA | 34.58000 |
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| LogP | 9.63300 |
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| Index of Refraction | 1.518 |
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| InChIKey | ZVXNYZWXUADSRV-UHFFFAOYSA-N |
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| SMILES | CCCCCCCCN=c1ccn(CCCCCCCCCCn2ccc(=NCCCCCCCC)cc2)cc1 |
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Synonyms
| Octeniderm |
| 1,1'-(1,10-Decanediyl)bis[1,4-dihydro-4-(octylimino)pyridine] |
| 1,1'-Decamethylenebis(1,4-dihydro-4-(octylimino)pyridine) |
| Octenisept |
| NeoKodan |
