Introduction：Basic information about CAS 71897-07-9|2-Phenyl-6,7-dimethylquinoxaline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-Phenyl-6,7-dimethylquinoxaline |
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| CAS Number | 71897-07-9 | Molecular Weight | 234.296 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 398.3±37.0 °C at 760 mmHg |
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| Molecular Formula | C16H14N2 | Melting Point | / |
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| MSDS | / | Flash Point | 172.4±17.8 °C |
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Names
| Name | 6,7-dimethyl-2-phenylquinoxaline |
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| Synonym | More Synonyms |
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2-Phenyl-6,7-dimethylquinoxaline BiologicalActivity
| Description | AG 1295 is a selective platelet-derived growth factor receptor (PDGFR) tyrosine-kinase inhibitor. AG 1295 reduces neointimal formation in aortic allograft vasculopathy by inhibition of PDGFR-beta-triggered tyrosine phosphorylation[1][2]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Protein Tyrosine Kinase/RTK >>PDGFR |
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| Target | PDGFR[1] |
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| References | [1]. Zheng Y, et al. Platelet-derived growth factor receptor kinase inhibitor AG1295 and inhibition of experimental proliferative vitreoretinopathy. Jpn J Ophthalmol. 2003 Mar-Apr;47(2):158-65. [2]. Inhibition of aortic allograft vasculopathy by local delivery of platelet-derived growth factor receptor tyrosine-kinase blocker AG-1295. Transplantation. 2002 Nov 15;74(9):1335-41. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 398.3±37.0 °C at 760 mmHg |
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| Molecular Formula | C16H14N2 |
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| Molecular Weight | 234.296 |
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| Flash Point | 172.4±17.8 °C |
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| Exact Mass | 234.115692 |
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| PSA | 25.78000 |
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| LogP | 3.92 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.636 |
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| InChIKey | FQNCLVJEQCJWSU-UHFFFAOYSA-N |
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| SMILES | Cc1cc2ncc(-c3ccccc3)nc2cc1C |
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| Storage condition | −20°C |
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Safety Information
| Safety Phrases | S22;S24/25 |
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| WGK Germany | 3 |
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| HS Code | 2933990090 |
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Customs
| HS Code | 2933990090 |
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| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| AG 1295 |
| 2-Phenyl-6,7-dimethylquinoxaline |
| F1284-0835 |
| TYRPHOSTIN AG 1295 |
| 6,7-Dimethyl-2-phenylquinoxaline |
| 6,7-dimethyl-2-phenyl-quinoxaline |
| Quinoxaline, 6,7-dimethyl-2-phenyl- |
| 6,7-Dimethyl-2-phenyl-chinoxalin |
