CAS 25137-01-3|(R)-(-)-NIPECOTIC ACID ETHYL ESTER

Introduction:Basic information about CAS 25137-01-3|(R)-(-)-NIPECOTIC ACID ETHYL ESTER, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(R)-(-)-NIPECOTIC ACID ETHYL ESTER
CAS Number25137-01-3Molecular Weight157.210
Density1.0±0.1 g/cm3Boiling Point238.6±0.0 °C at 760 mmHg
Molecular FormulaC8H15NO2Melting Point/
MSDSChineseUSAFlash Point90.6±0.0 °C
Symbol
GHS05, GHS07
Signal WordDanger

Names

NameEthyl (3R)-piperidine-3-carboxylate
SynonymMore Synonyms

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point238.6±0.0 °C at 760 mmHg
Molecular FormulaC8H15NO2
Molecular Weight157.210
Flash Point90.6±0.0 °C
Exact Mass157.110275
PSA38.33000
LogP0.96
Vapour Pressure0.0±0.4 mmHg at 25°C
Index of Refraction1.449
InChIKeyXIWBSOUNZWSFKU-SSDOTTSWSA-N
SMILESCCOC(=O)C1CCCNC1
Storage conditionRefrigerator

Safety Information

Symbol
GHS05, GHS07
Signal WordDanger
Hazard StatementsH315-H318-H335
Precautionary StatementsP261-P280-P305 + P351 + P338
Personal Protective EquipmentEyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard CodesXi
Risk Phrases36/37/38-41-37/38
Safety PhrasesS26-S36/37/39-S39-S36
RIDADRNONH for all modes of transport
HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles7

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THIP analgesia: cross tolerance with morphine.

Life Sci. 32(19) , 2265-72, (1983)

THIP (4,5,6,7-tetrahydroisoxazolo (5,4-c) pyridone-3-ol), a direct acting GABA receptor agonist, has been shown to have antinociceptive properties. To determine whether tolerance develops to the analg...

(R)-nipecotic acid ethyl ester: a direct-acting cholinergic agonist that displays greater efficacy at M2 than at M1 muscarinic receptors.

J. Pharmacol. Exp. Ther. 242(1) , 173-8, (1987)

Previous reports have suggested that the ethyl ester of (R)-nipecotic acid ethyl ester [(R)-NAEE] displays cholinomimetic properties in vivo. The present study was undertaken to characterize more full...

Differential effects of ethyl (R,S)-nipecotate on the behaviors of highly and minimally aggressive female golden hamsters.

Psychopharmacology 89(4) , 444-8, (1986)

The GABA uptake inhibitor ethyl (R,S)-nipecotate produces a dose-dependent suppression of aggression in highly aggressive hamsters but not in minimally aggressive ones. This suppression occurs at dose...

Synonyms

(R)-Ethyl nipecotate
Ethyl (R)-3-Piperidinecarboxylate
(R)-Ethylpiperidine-3-carboxylate
Ethyl (R)-nipecotate
(R)-(-)-Nipecotic Acid Ethyl Ester
(R)-(-)-Ethyl nipecotate
(R)-Nipecotic acid ethyl ester
ethyl R-nipecotate
Ethyl (R)-(-)-piperidine-3-carboxylate
(R)-(-)-3-Piperidinecarboxylic Acid Ethyl Ester
3-Piperidinecarboxylic acid, ethyl ester, (3R)-
Ethyl (R)-(-)-3-Piperidinecarboxylate
Ethyl (R)-(-)-Nipecotate
MFCD03093637
Ethyl (3R)-3-piperidinecarboxylate
Ethyl (3R)-piperidine-3-carboxylate
(R)-Ethyl piperidine-3-carboxylate
D-Nipecotic acid ethyl ester
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