CAS 251634-21-6|Dynamin inhibitory peptide

Introduction:Basic information about CAS 251634-21-6|Dynamin inhibitory peptide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDynamin inhibitory peptide
CAS Number251634-21-6Molecular Weight1121.25000
Density/Boiling Point/
Molecular FormulaC47H80N18O14Melting Point/
MSDS/Flash Point/

Names

NameDynamin inhibitory peptide

Dynamin inhibitory peptide BiologicalActivity

DescriptionDynamin inhibitory peptide competitively blocks binding of dynamin to amphiphysin, thus preventing endocytosis. Dynamin inhibitory peptide blocks the dopamine D3 effect on GABAA receptors[1].
Related CatalogResearch Areas >>Neurological DiseaseSignaling Pathways >>Cytoskeleton >>Dynamin
In VitroDynamin inhibitory peptide (50 μM) inhibits GABAAR endocytosis[1].
References

[1]. Guojun Chen, et al. Dopamine D3 receptors regulate GABAA receptor function through a phospho-dependent endocytosis mechanism in nucleus accumbens. J Neurosci. 2006 Mar 1;26(9):2513-21.

Chemical & Physical Properties

Molecular FormulaC47H80N18O14
Molecular Weight1121.25000
Exact Mass1120.61000
PSA529.06000
InChIKeyLHQOQXYEPUSHJL-LNIRUYPRSA-N
SMILESCC(NC(=O)C(CCCN=C(N)N)NC(=O)C(CC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C(CO)NC(=O)C1CCCN1C(=O)C(NC(=O)C(N)CCC(N)=O)C(C)C)C(=O)N1CCCC1C(=O)O
Storage condition-20°C
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