Introduction：Basic information about CAS 391901-45-4|(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (R)-2-((4-Aminophenethyl)amino)-1-phenylethanol |
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| CAS Number | 391901-45-4 | Molecular Weight | 256.34 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 447.9±24.0 °C at 760 mmHg |
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| Molecular Formula | C16H20N2O | Melting Point | / |
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| MSDS | / | Flash Point | 224.7±22.9 °C |
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Names
| Name | (alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]-benzenemethanol |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | Mirabegron impurity-1 is a potent and selectiveβ3- adrenergic receptor agonist. Mirabegron impurity-1has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used inthe study of the treatment of bladder impurity [1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| References | [1]. Takusagawa S, et al. Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist. Xenobiotica. 2012 Oct;42(10):957-67. |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 447.9±24.0 °C at 760 mmHg |
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| Molecular Formula | C16H20N2O |
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| Molecular Weight | 256.34 |
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| Flash Point | 224.7±22.9 °C |
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| Exact Mass | 256.157562 |
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| PSA | 58.28000 |
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| LogP | 1.45 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.618 |
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| InChIKey | TUAHDMSPHZSMQN-INIZCTEOSA-N |
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| SMILES | Nc1ccc(CCNCC(O)c2ccccc2)cc1 |
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Synonyms
| Benzenemethanol, α-[[[2-(4-aminophenyl)ethyl]amino]methyl]-, (αR)- |
| (1R)-2-[[2-(4-aminophenyl)ethyl]amino]-1-phenylethanol |
| (R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol |
| (R)-2-(4-aminophenylethylamine)-1-phenylethanol |
| Mirabegron Impurity 6 |
| YM-208876 |
| (R)-2-[[2-(4-aminophenyl)ethyl]amino]-1-phenylethanol |
| (1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol |
| (1 R)-2-[(4-aminophenethyl)amino]-1-phenyl-1-ethanol |
