Introduction：Basic information about CAS 1392-21-8|Kitasamycin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Kitasamycin |
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| CAS Number | 1392-21-8 | Molecular Weight | 785.958 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 874.7±65.0 °C at 760 mmHg |
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| Molecular Formula | C40H67NO14 | Melting Point | / |
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| MSDS | / | Flash Point | 482.8±34.3 °C |
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Names
| Name | Kitasamycin |
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| Synonym | More Synonyms |
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Kitasamycin BiologicalActivity
| Description | Leucomycin (kitasamycin) is a macrolide antibiotic produced by Streptomyces kitasatoensis[1][2][3][4]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| References | [1]. PACHTMAN EA, et al. Leucomycin; a new antibiotic. Am J Pharm Sci Support Public Health. 1958 Oct;130(10):342-4. [2]. Vézina C, et al. Biosynthesis of kitasamycin (leucomycin) by leucine analog-resistant mutants of Streptomyces kitasatoensis. Antimicrob Agents Chemother. 1979 May;15(5):738-46. [3]. La T, et al. Testing the efficacy of kitasamycin for use in the control and treatment of swine dysentery in experimentally infected pigs. Aust Vet J. 2019 Sep 17. [4]. Hassan AB, et al. Pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers. Dtsch Tierarztl Wochenschr. 1990 Aug;97(8):315-7. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 874.7±65.0 °C at 760 mmHg |
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| Molecular Formula | C40H67NO14 |
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| Molecular Weight | 785.958 |
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| Flash Point | 482.8±34.3 °C |
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| Exact Mass | 785.456177 |
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| LogP | 3.35 |
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| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
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| Index of Refraction | 1.541 |
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| InChIKey | XYJOGTQLTFNMQG-UHFFFAOYSA-N |
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| SMILES | COC1C(O)CC(=O)OC(C)CC=CC=CC(O)C(C)CC(CC=O)C1OC1OC(C)C(OC2CC(C)(O)C(O)C(C)O2)C(N(C)C)C1O |
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| Storage condition | 2-8°C |
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| Water Solubility | ethanol: 50 mg/mL, clear to slightly hazy, light-yellow |
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Safety Information
| Hazard Codes | Xi |
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| Safety Phrases | 24/25 |
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| WGK Germany | 1 |
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| RTECS | WG9400000 |
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Synonyms
| (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-Dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate (non-preferred name) |
| Ayermycin |
| 3-Deacetyljosamycin |
| Sineptina |
| Syneptine |
| (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-Dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 3-methylbutanoate |
| EINECS 232-429-6 |
| 3-O-Deacetyljosamycin |
| Kitasamycin |
| Leucomycin A1 |
| Stereomycine |
