CAS 168650-46-2|(Asp371)-Tyrosinase (369-377) (human) acetate salt

Introduction：Basic information about CAS 168650-46-2|(Asp371)-Tyrosinase (369-377) (human) acetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	(Asp371)-Tyrosinase (369-377) (human) acetate salt
CAS Number	168650-46-2	Molecular Weight	1031.161
Density	1.4±0.1 g/cm3	Boiling Point	1578.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₂H₆₆N₁₀O₁₆S₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	908.2±34.3 °C

Names

Name	L-Tyrosyl-L-Methionyl-L-alpha-Aspartylglycyl-L-Threonyl-L-Methionyl-L-Seryl-L-Glutaminyl-L-Valine
Synonym	More Synonyms

BiologicalActivity

Description	Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47. [2]. Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86.

Description

Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy[1][2].

Related Catalog

Research Areas >>CancerSignaling Pathways >>Others >>Others

References

[1]. Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47.

[2]. Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86.

Chemical & Physical Properties

Density	1.4±0.1 g/cm3
Boiling Point	1578.2±65.0 °C at 760 mmHg
Molecular Formula	C₄₂H₆₆N₁₀O₁₆S₂
Molecular Weight	1031.161
Flash Point	908.2±34.3 °C
Exact Mass	1030.409912
LogP	-1.38
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.590
InChIKey	TWALUFAMCVRLBU-UHFFFAOYSA-N
SMILES	CSCCC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CC(=O)O)C(=O)NCC(=O)NC(C(=O)NC(CCSC)C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(C(=O)O)C(C)C)C(C)O.O=C(O)C(F)(F)F

Safety Information

RIDADR	NONH for all modes of transport

Synonyms

L-Valine, L-tyrosyl-L-methionyl-L-α-aspartylglycyl-L-threonyl-L-methionyl-L-seryl-L-glutaminyl-

L-Tyrosyl-L-methionyl-L-α-aspartylglycyl-L-threonyl-L-methionyl-L-seryl-L-glutaminyl-L-valine

Tyrosinase

YMDGTMSQV

(Asp371)-Tyrosinase (369-377) (human)

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