CAS 63968-82-1|Kassinin

Introduction:Basic information about CAS 63968-82-1|Kassinin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameKassinin
CAS Number63968-82-1Molecular Weight1335.525
Density1.3±0.1 g/cm3Boiling Point1714.5±65.0 °C at 760 mmHg
Molecular FormulaC59H95N15O18SMelting Point/
MSDS/Flash Point990.7±34.3 °C

Names

NameKassinin
SynonymMore Synonyms

Kassinin BiologicalActivity

DescriptionKassinin is a peptide derived from the Kassina frog. It belongs to tachykinin family of neuropeptides. It is secreted as a defense response, and is involved in neuropeptide signalling.
Related CatalogSignaling Pathways >>GPCR/G Protein >>Neurokinin ReceptorSignaling Pathways >>Neuronal Signaling >>Neurokinin ReceptorNatural Products >>OthersPeptidesResearch Areas >>Neurological Disease
In VitroAmino acid composition and sequence of Kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis. Methanol extracts of the skin of the African amphibian Kassina senegalensis contain a dodecapeptide, Kassinin, belonging to the family of tachykinins or physalaemin-like peptides. Kassinin, like all other natural tachykinins, possesses the characteristic C-terminal tripeptide Gly-Leu-Met-NH2 and a phenylalanine residue in position 5 from the C-terminus. The amino acid sequence in the N-moiety of the molecule differs sharply from that of the other tachykinins[1].
References

[1]. Anastasi A, et al. Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis. Experientia. 1977 Jul 15;33(7):857-8.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point1714.5±65.0 °C at 760 mmHg
Molecular FormulaC59H95N15O18S
Molecular Weight1335.525
Flash Point990.7±34.3 °C
Exact Mass1334.654053
LogP0.20
Vapour Pressure0.0±0.3 mmHg at 25°C
Index of Refraction1.571
InChIKeyNXTPETCPVNEEOP-UHFFFAOYSA-N
SMILESCSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(N)=O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C1CCCN1C(=O)C(NC(=O)C(N)CC(=O)O)C(C)C)C(C)C)C(N)=O
Storage condition2-8℃

Synonyms

L-Methioninamide, L-α-aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-α-aspartyl-L-α-glutamyl-L-phenylalanyl-L-valylglycyl-L-leucyl-
Asp-Val-Pro-Lys-Ser-Asp-Gln-Phe-Val-Gly-Leu-Met-NH2
Kassinin
L-α-Aspartyl-L-valyl-L-prolyl-L-lysyl-L-seryl-L-α-aspartyl-L-α-glutamyl-L-phenylalanyl-L-valylglycyl-L-leucyl-L-methioninamide
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